Rémi Brazeilles

TL;DR: IBS symptom severity is found to be associated negatively with microbial richness, exhaled CH4, presence of methanogens, and enterotypes enriched with Clostridiales or Prevotella species.

TL;DR: Consumption of a fermented milk product containing dairy starters and Bifidobacterium animalis potentiates colonic short chain fatty acids production and decreases abundance of a pathobiont Bilophila wadsworthia compared to a milk product in subjects with irritable bowel syndrome is shown.

TL;DR: The concept that allochthonous bacteria have transient and subject-specific effects on the gut microbiome that can be leveraged to re-engineer the gut microbiota and improve dysbiosis-related diseases is supported.

TL;DR: MixMC as discussed by the authors is a multivariate data analysis framework for metagenomic biomarker discovery, which accounts for the compositional nature of 16S data and enables detection of subtle differences when high inter-subject variability is present due to microbial sampling performed repeatedly on the same subjects, but in multiple habitats.

TL;DR: Results support the concept of brain-gut-microbiota interactions in healthy humans and are needed to inform preclinical reports that microbial modulation may affect mood and behavior.