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Ren-Xi Zhuo
Researcher at Wuhan University
Publications - 457
Citations - 17875
Ren-Xi Zhuo is an academic researcher from Wuhan University. The author has contributed to research in topics: Micelle & Drug delivery. The author has an hindex of 62, co-authored 457 publications receiving 16207 citations.
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Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers
TL;DR: In this article, the authors present a review of the recent developments in this field, and focus on two categories of PNIPAAm-based copolymer micelles as smart drug delivery systems.
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Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery.
Jing Zhang,Zhefan Yuan,Ya Wang,Wei-Hai Chen,Guo-Feng Luo,Si-Xue Cheng,Ren-Xi Zhuo,Xian-Zheng Zhang +7 more
TL;DR: A novel type of cellular-uptake-shielding multifunctional envelope-type mesoporous silica nanoparticle designed for tumor-triggered targeting drug delivery to cancerous cells was designed and in vitro study demonstrated that MEMSN was shielded against normal cells.
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Design and development of polymeric micelles with cleavable links for intracellular drug delivery
TL;DR: This review highlights the recent advance in this field and focuses on two types of polymeric micelles that can respond to the physiological signals, i.e., intracellular pH- and reduction-sensitive micells.
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Construction of functional aliphatic polycarbonates for biomedical applications
TL;DR: The present review outlines the development up to date concerning the design and biomedical application of functional aliphatic polycarbonates, with an emphasis on their ring-opening (co)polymerization preparation.
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Dual-pH Sensitive Charge-Reversal Polypeptide Micelles for Tumor-Triggered Targeting Uptake and Nuclear Drug Delivery
Shisong Han,Ze-Yong Li,Jing-Yi Zhu,Kai Han,Zhengyang Zeng,Wei Hong,Wenxin Li,Hui-Zhen Jia,Yun Liu,Ren-Xi Zhuo,Xian-Zheng Zhang +10 more
TL;DR: A novel dual-pH sensitive charge-reversal strategy that facilitates tumor targeting and nuclear delivery simultaneously by simply modifying the lysine amino residues of polylysine and Tat into two different pH-sensitive β-carboxylic amides.