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René L. Warren

Researcher at BC Cancer Agency

Publications -  121
Citations -  10250

René L. Warren is an academic researcher from BC Cancer Agency. The author has contributed to research in topics: Sequence assembly & Genome. The author has an hindex of 35, co-authored 98 publications receiving 8639 citations. Previous affiliations of René L. Warren include BC Cancer Research Centre & McGill University.

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Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

TL;DR: Overabundance of Fusobacterium sequences in tumor versus matched normal control tissue is verified by quantitative PCR analysis from a total of 99 subjects, and a positive association with lymph node metastasis is observed.
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The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

TL;DR: The tissue‐restricted GATA‐4 transcription factor and Nkx2‐5 homeodomain protein are two early markers of precardiac cells and the GATA/Nkx partnership may represent a paradigm for transcription factor interaction during organogenesis.
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Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

TL;DR: For 515 patients from six tumor sites, RNA-seq data from The Cancer Genome Atlas was used to identify mutations that were predicted to be immunogenic in that they yielded mutational epitopes presented by the MHC proteins encoded by each patient's autologous HLA-A alleles that were associated with increased patient survival.