E
Ewan A. Gibb
Researcher at BC Cancer Agency
Publications - 100
Citations - 10379
Ewan A. Gibb is an academic researcher from BC Cancer Agency. The author has contributed to research in topics: Bladder cancer & Medicine. The author has an hindex of 29, co-authored 80 publications receiving 7401 citations. Previous affiliations of Ewan A. Gibb include University of Western Ontario & University of British Columbia.
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Journal ArticleDOI
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer
A. Gordon Robertson,Jaegil Kim,Hikmat Al-Ahmadie,Joaquim Bellmunt,Guangwu Guo,Andrew D. Cherniack,Toshinori Hinoue,Peter W. Laird,Katherine A. Hoadley,Rehan Akbani,Mauro A. A. Castro,Ewan A. Gibb,Rupa S. Kanchi,Dmitry A. Gordenin,Sachet A. Shukla,Francisco Sanchez-Vega,Donna E. Hansel,Bogdan Czerniak,Victor E. Reuter,Xiaoping Su,Benilton S. Carvalho,Vinicius S Chagas,Karen Mungall,Sara Sadeghi,Chandra Sekhar Pedamallu,Yiling Lu,Leszek J. Klimczak,Jiexin Zhang,Caleb Choo,Akinyemi I. Ojesina,Susan Bullman,Kristen M. Leraas,Tara M. Lichtenberg,Catherine J. Wu,N. Schultz,Gad Getz,Matthew Meyerson,Gordon B. Mills,David J. McConkey,Monique Albert,Iakovina Alexopoulou,Adrian Ally,Tatjana Antic,Manju Aron,Miruna Balasundaram,John M. S. Bartlett,Stephen B. Baylin,Allison Beaver,Inanc Birol,Lori Boice,Moiz S. Bootwalla,Jay Bowen,Reanne Bowlby,Denise Brooks,Bradley M. Broom,Wiam Bshara,Eric J. Burks,Flavio Mavignier Carcano,Rebecca Carlsen,André Lopes Carvalho,Eric P. Castle,Patricia Castro,James W.F. Catto,David Chesla,Eric Chuah,Sudha Chudamani,Victoria K. Cortessis,Sandra Cottingham,Daniel Crain,Erin Curley,Siamak Daneshmand,John A. Demchok,Noreen Dhalla,Hooman Djaladat,John Eckman,Sophie C. Egea,Jay Engel,Ina Felau,Martin L. Ferguson,Johanna Gardner,Julie M. Gastier-Foster,Mark Gerken,Carmen Gomez-Fernandez,Jodi Harr,Arndt Hartmann,Lynn M. Herbert,Thai H. Ho,Robert A. Holt,Carolyn M. Hutter,Steven J.M. Jones,Merce Jorda,Richard J. Kahnoski,Katayoon Kasaian,David J. Kwiatkowski,Phillip H. Lai,Brian R. Lane,Seth P. Lerner,Jia Liu,Laxmi Lolla,Yair Lotan,Fabiano R. Lucchesi,Yussanne Ma,Roberto Dias Machado,Dennis T. Maglinte,David Mallery,Marco A. Marra,Sue E. Martin,Michael Mayo,Anoop Meraney,Alireza Moinzadeh,Richard A. Moore,Edna M. Mora Pinero,Scott Morris,Carl Morrison,Andrew J. Mungall,Jerome Myers,Rashi Naresh,Peter H. O'Donnell,Dipen J. Parekh,Jeremy Parfitt,Joseph Paulauskis,Robert Penny,Todd Pihl,Sima P. Porten,Mario Quintero-Aguilo,Nilsa C. Ramirez,W. Kimryn Rathmell,Kimberly M. Rieger-Christ,Charles Saller,Andrew Salner,George E. Sandusky,Cristovam Scapulatempo-Neto,Jacqueline E. Schein,Anne Schuckman,Candace Shelton,Troy Shelton,Jeff Simko,Parminder Singh,Payal Sipahimalani,Norm D. Smith,Heidi J. Sofia,Andrea Sorcini,Melissa L. Stanton,Gary D. Steinberg,Robert Stoehr,Travis Sullivan,Qiang Sun,Angela Tam,Roy Tarnuzzer,Katherine Tarvin,Helge Taubert,Nina Thiessen,Leigh B. Thorne,Kane Tse,Kelinda Tucker,David Van Den Berg,Kim E.M. van Kessel,Sven Wach,Yunhu Wan,Zhining Wang,John N. Weinstein,Daniel J. Weisenberger,Lisa Wise,Tina Wong,Ye Wu,Liming Yang,Leigh Anne Zach,Jean C. Zenklusen,Jiashan Zhang,Erik Zmuda,Ellen C. Zwarthoff +170 more
TL;DR: An analysis of 412 muscle-invasive bladder cancers characterized by multiple TCGA analytical platforms identified 5 expression subtypes that may stratify response to different treatments and identified a poor-survival "neuronal" subtype in which the majority of tumors lacked small cell or neuroendocrine histology.
Journal ArticleDOI
The functional role of long non-coding RNA in human carcinomas
TL;DR: The emerging functional role of lncRNAs in human cancer is highlighted and molecular mechanisms by which these RNA species function are described, providing insight into the functional roles they may play in tumorigenesis.
Journal ArticleDOI
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
Benjamin J. Raphael,Ralph H. Hruban,Andrew J. Aguirre,Richard A. Moffitt,Jen Jen Yeh,Chip Stewart,A. Gordon Robertson,Andrew D. Cherniack,Manaswi Gupta,Gad Getz,Stacey Gabriel,Matthew Meyerson,Carrie Cibulskis,Suzanne S. Fei,Toshinori Hinoue,Hui Shen,Peter W. Laird,Shiyun Ling,Yiling Lu,Gordon B. Mills,Rehan Akbani,Phillipe Loher,Eric Londin,Isidore Rigoutsos,Aristeidis G. Telonis,Ewan A. Gibb,Anna Goldenberg,Aziz M. Mezlini,Katherine A. Hoadley,Eric A. Collisson,Eric S. Lander,Bradley A. Murray,Julian M. Hess,Mara Rosenberg,Louis Bergelson,Hailei Zhang,Juok Cho,Grace Tiao,Jaegil Kim,Dimitri Livitz,Ignaty Leshchiner,Brendan Reardon,Eliezer M. Van Allen,Atanas Kamburov,Rameen Beroukhim,Gordon Saksena,Steven E. Schumacher,Michael S. Noble,David I. Heiman,Nils Gehlenborg,Michael S. Lawrence,Volkan Adsay,Gloria M. Petersen,David S. Klimstra,Nabeel Bardeesy,Mark D.M. Leiserson,Reanne Bowlby,Katayoon Kasaian,Inanc Birol,Karen Mungall,Sara Sadeghi,John N. Weinstein,Paul T. Spellman,Yuexin Liu,Laufey T. Amundadottir,Joel E. Tepper,Aatur D. Singhi,Rajiv Dhir,Drwiega Paul,Thomas C. Smyrk,Lizhi Zhang,Paula Kim,Jay Bowen,Jessica Frick,Julie M. Gastier-Foster,Mark Gerken,Kevin Lau,Kristen M. Leraas,Tara M. Lichtenberg,Nilsa C. Ramirez,Jeremy Renkel,Mark E. Sherman,Lisa Wise,Peggy Yena,Erik Zmuda,Juliann Shih,Adrian Ally,Miruna Balasundaram,Rebecca Carlsen,Andy Chu,Eric Chuah,Amanda Clarke,Noreen Dhalla,Robert A. Holt,Steven J.M. Jones,Darlene Lee,Yussanne Ma,Marco A. Marra,Michael Mayo,Richard A. Moore,Andrew J. Mungall,Jacqueline E. Schein,Payal Sipahimalani,Angela Tam,Nina Thiessen,Kane Tse,Tina Wong,Denise Brooks,J. Todd Auman,Saianand Balu,Tom Bodenheimer,D. Neil Hayes,Alan P. Hoyle,Stuart R. Jefferys,Corbin D. Jones,Shaowu Meng,Piotr A. Mieczkowski,Lisle E. Mose,Charles M. Perou,Amy H. Perou,Jeffrey Roach,Yan Shi,Janae V. Simons,Tara Skelly,Matthew G. Soloway,Donghui Tan,Umadevi Veluvolu,Joel S. Parker,Matthew D. Wilkerson,Anil Korkut,Yasin Senbabaoglu,Patrick Burch,Robert R. McWilliams,Kari G. Chaffee,Ann L. Oberg,Wei Zhang,Marie-Claude Gingras,David A. Wheeler,Liu Xi,Monique Albert,John M. S. Bartlett,Harman Sekhon,Yeager Stephen,Zaren Howard,Miller Judy,Anne Breggia,Rachna T. Shroff,Sudha Chudamani,Jia Liu,Laxmi Lolla,Rashi Naresh,Todd Pihl,Qiang Sun,Yunhu Wan,Ye Wu,Smith Jennifer,Kevin Roggin,Karl-Friedrich Becker,Madhusmita Behera,Joseph J. Bennett,Lori Boice,Eric J. Burks,Carlos Gilberto Carlotti Junior,John Chabot,Daniela Pretti da Cunha Tirapelli,Jose Sebastião dos Santos,Michael Dubina,Jennifer M. Eschbacher,Mei Huang,Lori Huelsenbeck-Dill,Roger Jenkins,Alexey Karpov,Rafael Kemp,Vladimir Lyadov,Shishir K. Maithel,Georgy Manikhas,Eric Montgomery,Houtan Noushmehr,Adeboye O. Osunkoya,Taofeek K. Owonikoko,Oxana Paklina,Olga Potapova,Suresh S. Ramalingam,W. Kimryn Rathmell,Kimberly M. Rieger-Christ,Charles Saller,Galiya Setdikova,Alexey Shabunin,Gabriel Sica,Tao Su,Travis Sullivan,Pat Swanson,Katherine Tarvin,Michael Tavobilov,Leigh B. Thorne,Stefan Urbanski,Olga Voronina,Timothy C. Wang,Daniel Crain,Erin Curley,Johanna Gardner,David Mallery,Scott J. Morris,Joseph Paulauskis,Robert Penny,Candace Shelton,Troy Shelton,Klaus-Peter Janssen,Oliver F. Bathe,Nathan Bahary,Julia Slotta-Huspenina,Amber L. Johns,Hanina Hibshoosh,Rosa F. Hwang,Antonia R. Sepulveda,Amie Radenbaugh,Stephen B. Baylin,Mario Berrios,Moiz S. Bootwalla,Andrea Holbrook,Phillip H. Lai,Dennis T. Maglinte,Swapna Mahurkar,Timothy J. Triche,David Van Den Berg,Daniel J. Weisenberger,Lynda Chin,Raju Kucherlapati,Melanie H. Kucherlapati,Angeliki Pantazi,Peter J. Park,Doug Voet,Pei Lin,Scott Frazer,Timothy Defreitas,Sam Meier,Sun Young Kwon,Yong Hoon Kim,Sang Jae Park,Sung Sik Han,Seong Hoon Kim,Hark Kyun Kim,Emma E. Furth,Margaret A. Tempero,Chris Sander,Andrew V. Biankin,David K. Chang,Peter Bailey,Anthony J. Gill,James G. Kench,Sean M. Grimmond,Russell Postier,Rosemary E. Zuna,Hugues Sicotte,John A. Demchok,Martin L. Ferguson,Carolyn M. Hutter,Kenna R. Mills Shaw,Margi Sheth,Heidi J. Sofia,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jiashan Zhang,Ina Felau,Jean C. Zenklusen +265 more
TL;DR: An integrated multi-platform analysis of 150 pancreatic ductal adenocarcinoma specimens reveals a complex molecular landscape of PDAC and provides a roadmap for precision medicine.
Journal ArticleDOI
A Consensus Molecular Classification of Muscle-invasive Bladder Cancer.
Aurélie Kamoun,Aurélien de Reyniès,Yves Allory,Yves Allory,Gottfrid Sjödahl,A. Gordon Robertson,Roland Seiler,Katherine A. Hoadley,Clarice S. Groeneveld,Clarice S. Groeneveld,Hikmat Al-Ahmadie,Woonyoung Choi,Mauro A. A. Castro,Jacqueline Fontugne,Jacqueline Fontugne,Pontus Eriksson,Qianxing Mo,Jordan Kardos,Alexandre R. Zlotta,Arndt Hartmann,Colin Dinney,Joaquim Bellmunt,Thomas Powles,Núria Malats,Keith S. Chan,William Y. Kim,David J. McConkey,Peter C. Black,Lars Dyrskjøt,Mattias Höglund,Seth P. Lerner,Francisco X. Real,François Radvanyi,Mattias Aine,Isabelle Bernard-Pierrot,Bogdan Czerniak,Ewan A. Gibb,Jaegil Kim,David J. Kwiatkowski,Thierry Lebret,Fredrik Liedberg,Arlene O. Siefker-Radtke,Nanor Sirab,Ann Taber,John N. Weinstein +44 more
TL;DR: In this paper, a consensus set of six molecular classes (luminal papillary (24%), luminal nonspecified (8), luminal unstable (15), stroma-rich (15%), basal/squamous (35%), and neuroendocrine-like (3%) was identified.
Journal ArticleDOI
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Christopher J. Ricketts,Aguirre A. de Cubas,Huihui Fan,Christof C. Smith,Martin Lang,Ed Reznik,Reanne Bowlby,Ewan A. Gibb,Rehan Akbani,Rameen Beroukhim,Donald P. Bottaro,Toni K. Choueiri,Richard A. Gibbs,Andrew K. Godwin,Scott M. Haake,A. Ari Hakimi,Elizabeth P. Henske,James J. Hsieh,Thai H. Ho,Rupa S. Kanchi,Bhavani Krishnan,David J. Kwiatkowski,Wembin Lui,Maria Merino,Gordon B. Mills,Jerome Myers,Michael L. Nickerson,Victor E. Reuter,Laura S. Schmidt,C Simon Shelley,Hui Shen,Brian Shuch,Sabina Signoretti,Ramaprasad Srinivasan,Pheroze Tamboli,George Thomas,Benjamin G. Vincent,Cathy D. Vocke,David A. Wheeler,Lixing Yang,William Y. Kim,A. Gordon Robertson,Paul T. Spellman,W. Kimryn Rathmell,W. Marston Linehan +44 more
TL;DR: Comprehensive genomic and phenotypic analysis of the RCC subtypes reveals distinctive features of each subtype that provide the foundation for the development of subtype-specific therapeutic and management strategies for patients affected with these cancers.