Richard A. Shimkets

TL;DR: This map serves as a starting point for a systems biology modeling of multicellular organisms, including humans, and recapitulated known pathways, extended pathways, and uncovered previously unknown pathway components.

TL;DR: A new member of the PDGF family, PDGF D, which also requires proteolytic activation is identified and characterized, which indicates that PDGFR-α activation may result from PDG FR-α/β heterodimerization.

TL;DR: In this paper, the authors have discussed vectors, host cells, antibodies and recombinant methods for producing polypeptides and polynucleotides, as well as methods for using same.

TL;DR: An mRNA profiling technique for determining differential gene expression that utilizes, but does not require, prior knowledge of gene sequences is described, which permits high-throughput reproducible detection of most expressed sequences with a sensitivity of greater than 1 part in 100,000.

TL;DR: Findings reveal a novel function for angioarrestin as an angiogenesis inhibitor and indicate that the molecule may be a potential cancer therapeutic.