Loic Giot

TL;DR: Examination of large-scale yeast two-hybrid screens reveals interactions that place functionally unclassified proteins in a biological context, interactions between proteins involved in the same biological function, and interactions that link biological functions together into larger cellular processes.

TL;DR: This map serves as a starting point for a systems biology modeling of multicellular organisms, including humans, and recapitulated known pathways, extended pathways, and uncovered previously unknown pathway components.

TL;DR: On the basis of protein interactions, LYST appears to function as an adapter protein that may juxtapose proteins that mediate intracellular membrane fusion reactions, as well as to the molecular dissection of the CHS-associated cancer predisposition.

TL;DR: In this article, Purified complexes of at least two polypeptides and methods of using the same are provided, as well as nucleic acids encoding chimeric compounds and vectors and cells containing the same.

TL;DR: In this article, the authors provided complexes of at least two polypeptides from the yeast S. cerevisiae and methods of using the same, including chimeric complexes.