R
Richard T. Jaspers
Researcher at VU University Amsterdam
Publications - 163
Citations - 4349
Richard T. Jaspers is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Skeletal muscle & Medicine. The author has an hindex of 31, co-authored 137 publications receiving 3608 citations. Previous affiliations of Richard T. Jaspers include VU University Medical Center & Manchester Metropolitan University.
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Journal ArticleDOI
Attenuated increase in maximal force of rat medial gastrocnemius muscle after concurrent peak power and endurance training
Regula Furrer,Richard T. Jaspers,Hein L. Baggerman,Nathalie Bravenboer,Paul Lips,Arnold de Haan,Arnold de Haan +6 more
TL;DR: Even by using task-specific recruitment of the compartmentalized rat GM, additional endurance training interfered with the adaptive response of peak power training and attenuated the increase in maximal force after power training.
Journal ArticleDOI
Reinforcement versus Fluidization in Cytoskeletal Mechanoresponsiveness
Ramaswamy Krishnan,Chan Young Park,Yu-chun Lin,Jere Mead,Richard T. Jaspers,Xavier Trepat,Guillaume Lenormand,Dhananjay T. Tambe,Alexander V. Smolensky,Andrew H. Knoll,James P. Butler,Jeffrey J. Fredberg +11 more
TL;DR: It is shown here that in loading conditions expected in most physiological circumstances the localized reinforcement response fails to scale up to the level of homogeneous cell stretch; fluidization trumps reinforcement.
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The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?
TL;DR: New experimental data and an inventory of critical stimuli and state of activation of the signaling pathways involved in regulating contractile and metabolic protein turnover reveal higher capacity for protein synthesis in high compared to low oxidative fibers.
Journal ArticleDOI
Adaptation of muscle size and myofascial force transmission: a review and some new experimental results
TL;DR: This paper considers the literature and some new experimental results important for adaptation of muscle fiber cross‐sectional area and serial sarcomere number, finding that general rules for the regulation of adaptation cannot be derived.
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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
Hessel Honkoop,Dennis E. M. de Bakker,Alla Aharonov,Fabian Kruse,Avraham Shakked,Phong D. Nguyen,Cecilia de Heus,Laurence Garric,Mauro J. Muraro,Adam R. Shoffner,Federico Tessadori,Joshua Craiger Peterson,Wendy Noort,Alberto Bertozzi,Gilbert Weidinger,George Posthuma,Dominic Grün,Willem J van der Laarse,Judith Klumperman,Richard T. Jaspers,Kenneth D. Poss,Alexander van Oudenaarden,Eldad Tzahor,Jeroen Bakkers +23 more
TL;DR: It is found that the metabolic reprogramming of border zone cardiomyocytes is induced by Nrg1/ErbB2 signaling and is important for their proliferation and is demonstrated that glycolysis regulatesCardiomyocyte proliferation during heart regeneration.