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Robert H. Paul
Researcher at University of Missouri–St. Louis
Publications - 260
Citations - 10590
Robert H. Paul is an academic researcher from University of Missouri–St. Louis. The author has contributed to research in topics: Neurocognitive & Cognition. The author has an hindex of 59, co-authored 247 publications receiving 9253 citations. Previous affiliations of Robert H. Paul include University of Missouri & Washington University in St. Louis.
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Journal ArticleDOI
Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety
Justine M. Gatt,Charles B. Nemeroff,Carol Dobson-Stone,Carol Dobson-Stone,Carol Dobson-Stone,Robert H. Paul,Richard A. Bryant,Richard A. Bryant,Peter R. Schofield,Peter R. Schofield,Peter R. Schofield,Evian Gordon,Andrew H. Kemp,Leanne M. Williams +13 more
TL;DR: Findings are consistent with the correlation of depression and anxiety, yet suggest that partially differentiated gene–brain cognition pathways to these syndromes can be identified, even in a nonclinical sample, and may aid establishing an evidence base for more tailored intervention strategies.
Journal Article
Cognitive Aging, Executive Function, and Fractional Anisotropy: A Diffusion Tensor MR Imaging Study
TL;DR: A relationship between FA and a measure of executive function-a core cognitive component that is a key feature of cognitive aging is demonstrated and proposed that that FA may provide an early means for the detection of age-related cognitive change.
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Obesity is associated with reduced white matter integrity in otherwise healthy adults.
Kelly M. Stanek,Stuart M. Grieve,Stuart M. Grieve,Adam M. Brickman,Mayuresh S. Korgaonkar,Robert H. Paul,Ronald A. Cohen,John Gunstad,John Gunstad +8 more
TL;DR: Findings suggest a possible role for adiposity in WM dysfunction and associated cognitive deficits, and an interaction between obesity and aging processes on certain WM tracts in otherwise healthy adults.
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Independent Effects of HIV, Aging, and HAART on Brain Volumetric Measures
TL;DR: HIV associated volumetric reductions within the amygdala, caudate, and corpus callosum occurs despite HAART, and HIV and aging independently increase brain vulnerability.
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Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model.
Shoutang Wang,Meer Mustafa,Carla M. Yuede,Santiago Viveros Salazar,Philip Kong,Hua Long,Michael E. Ward,Siddiqui Omer Rizwan,Robert H. Paul,Susan Gilfillan,Adiljan Ibrahim,Herve Rhinn,Ilaria Tassi,Arnon Rosenthal,Tina Schwabe,Marco Colonna +15 more
TL;DR: It is demonstrated that a mAb specific for the human microglial receptor TREM2 induces microglia proliferation, ameliorates Aβ-induced pathology in a mouse model of Alzheimer’s disease, and can be given safely in a first-in-human phase I clinical trial.