R
Robert J. Siegel
Researcher at Cedars-Sinai Medical Center
Publications - 506
Citations - 25581
Robert J. Siegel is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Mitral regurgitation & Mitral valve. The author has an hindex of 75, co-authored 463 publications receiving 22687 citations. Previous affiliations of Robert J. Siegel include Northern General Hospital & University of California, Los Angeles.
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Journal ArticleDOI
American College of Cardiology Clinical Expert Consensus Document on Standards for Acquisition, Measurement and Reporting of Intravascular Ultrasound Studies (IVUS). A report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents.
Gary S. Mintz,Steven E. Nissen,William D. Anderson,Steven R. Bailey,Raimund Erbel,Peter J. Fitzgerald,Fausto J. Pinto,Kenneth Rosenfield,Robert J. Siegel,E. Murat Tuzcu,Paul G. Yock,Robert A. O'Rourke,Jonathan Abrams,Eric R. Bates,Bruce R. Brodie,Pamela S. Douglas,Gabriel Gregoratos,Mark A. Hlatky,Judith S. Hochman,Sanjiv Kaul,Cynthia M. Tracy,David D. Waters,William L. Winters +22 more
TL;DR: In this article, the authors present an Expert Consensus Document that includes evidence about the standards for the acquisition, measurement, and reporting of intravascular ultrasound studies (IVUS).
Journal ArticleDOI
Percutaneous Repair or Surgery for Mitral Regurgitation
Ted Feldman,Elyse Foster,Donald D. Glower,Saibal Kar,Michael J. Rinaldi,Peter S. Fail,Richard W. Smalling,Robert J. Siegel,Geoffrey A. Rose,Eric Engeron,Catalin Loghin,Alfredo Trento,Eric R. Skipper,Tommy Fudge,George V. Letsou,Joseph M. Massaro,Laura Mauri +16 more
TL;DR: Although percutaneous repair was less effective at reducing mitral regurgitation than conventional surgery, the procedure was associated with superior safety and similar improvements in clinical outcomes.
Journal ArticleDOI
Transcatheter Aortic-Valve Replacement for Inoperable Severe Aortic Stenosis
Raj Makkar,Gregory P. Fontana,Hasan Jilaihawi,Samir R. Kapadia,Augusto D. Pichard,Pamela S. Douglas,Vinod H. Thourani,Vasilis Babaliaros,John G. Webb,Howard C. Herrmann,Joseph E. Bavaria,Susheel Kodali,David L. Brown,Bruce Bowers,Todd M. Dewey,Lars G. Svensson,Murat Tuzcu,Jeffrey W. Moses,Matthew R. Williams,Robert J. Siegel,Jodi J. Akin,William N. Anderson,Stuart J. Pocock,Craig R. Smith,Martin B. Leon +24 more
TL;DR: Among appropriately selected patients with severe aortic stenosis who were not suitable candidates for surgery, TAVR reduced the rates of death and hospitalization, with a decrease in symptoms and an improvement in valve hemodynamics that were sustained at 2 years of follow-up.
Journal ArticleDOI
Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial
Kohei Shitara,Mustafa Ozguroglu,Yung-Jue Bang,Maria Di Bartolomeo,Mario Mandalà,Min-Hee Ryu,Lorenzo Fornaro,Tomasz Olesinski,Christian Caglevic,Hyun Cheol Chung,Kei Muro,Eray Goekkurt,Wasat Mansoor,Raymond S. McDermott,Einat Shacham-Shmueli,X. Chen,Carlos Alberto Mayo,S. Peter Kang,Atsushi Ohtsu,Charles S. Fuchs,Guillermo Lerzo,Juan Manuel O'Connor,Guillermo Mendez,James Lynam,Niall C. Tebbutt,Mark Wong,Andrew Strickland,Chris Karapetis,David Goldstein,Paul Vasey,Jean-Luc Van Laethem,Eric Van Cutsem,Scott R. Berry,Mark Vincent,Bettina Muller,Felipe Rey,Angela Zambrano,Joaquin Guerra,Merete Krogh,Lene Baeksgaard,Mette Karen Yilmaz,Anneli Elme,Andrus Magi,Paivi Auvinen,Tuomo Alanko,Markus Moehler,Volker Kunzmann,Thomas Seufferlein,Peter C. Thuss-Patience,Thomas Hoehler,Georg Martin Haag,Salah-Eddin Al-Batran,Hugo Castro,Karla Lopez,Mynor Aguilar Vasquez,Mario Sandoval,Ka On Lam,Sinead Cuffe,Cathy Kelly,Ravit Geva,Ayala Hubert,Alex Beny,Baruch Brenner,Aprile Giuseppe,Alfredo Falcone,Evaristo Maiello,Rodolfo Passalacqua,Vincenzo Montesarchio,Hiroki Hara,Keisho Chin,Tomohiro Nishina,Yoshito Komatsu,Nozumo Machida,Shuichi Hironaka,Taroh Satoh,Takao Tamura,Naotaoshi Sugimoto,Haruhiko Cho,Yashushi Omuro,Ken Kato,Masahiro Goto,Ichinosuke Hyodo,Kazuhiro Yoshida,Hideo Baba,Taito Esaki,Junji Furuse,Wan Zamaniah Wan Mohammed,Carlos Hernandez Hernandez,Juan Casas Garcia,Adriana Dominguez Andrade,Katriona Clarke,Geir Hjortland,Nils Glenjen,Tomasz Kubiatowski,Jassem Jacek,Marek Z. Wojtukiewicz,Sergey Alexandrovich Lazarev,Yuri Lancukhay,Sergey Afanasayev,Vladimir Moiseyenko,Vladimir Kostorov,Svetlana Protsenko,Vadim Shirinkin,Dina Sakaeva,Natalia Fadeeva,Wei Peng Yong,Chau Hsien Matthew Ng,Barbara Robertson,Bernardo Rapaport,Graham Cohen,Lydia Dreosti,Paul Ruff,Conrad Jacobs,Gregory Landers,Waldemar Szpak,Sang-Young Roh,Jeeyun Lee,Yeul Hong Kim,Hyun Cheol Chung,Maria Alsina Maqueda,Federico Longo Munoz,Andres Cervantes Aguilar,Enrique Aranda Aguilar,Pilar Garcia Alfonso,Fernando Rivera,Jaime Feliu Batle,Roberto Pazo Cid,Kun-Huei Yeh,Jen-Shi Chen,Yee Chao,Chia Jui Yen,Oguz Kara,Suayib Yalcin,Daniel Hochhauser,Ian Chau,Al B. Benson,Veena Shankaran,Walid Shaib,Philip A. Philip,Vivek Sharma,Robert J. Siegel,Weijing Sun,Zev A. Wainberg,Ben George,Andrea J. Bullock,Samuel Myrick,Josephine Faruol,Richard M. Siegel,Timothy V. Larson,Carlos Becerra,Suresh Ratnam,Donald A. Richards,Stephen L. Riche +152 more
TL;DR: Pembrolizumab did not significantly improve overall survival compared with paclitaxel as second-line therapy for advanced gastric or gastro-oesophageal junction cancer with PD-L1 CPS of 1 or higher and had a better safety profile than pac litaxel.
Journal ArticleDOI
Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study
Tarun Chakravarty,Lars Søndergaard,John D. Friedman,Ole De Backer,Daniel S. Berman,Klaus F. Kofoed,Hasan Jilaihawi,Takahiro Shiota,Yigal Abramowitz,Troels H. Jørgensen,Tanya Rami,Sharjeel Israr,Gregory P. Fontana,Martina Chantal de Knegt,Andreas Fuchs,Patrick D. Lyden,Alfredo Trento,Deepak L. Bhatt,Martin B. Leon,Raj Makkar,Danny Ramzy,Wen Cheng,Robert J. Siegel,Louise M Thomson,Geeteshwar Mangat,Babak Hariri,Fadi J. Sawaya,Helle K. Iversen +27 more
TL;DR: Subclinical leaflet thrombosis was associated with increased rates of transient ischaemic attacks on the basis of two registries of patients who had CT imaging done after TAVR or SAVR and persisted in 20 (91%) of 22 patients not receiving anticoagulants.