Robert S. Bell

TL;DR: In this paper, a translocation involving a single gene family, consisting of EWS and related genes, has been identified in five different sarcomas, and its chimeric protein products could prove similarly amenable to inhibitors.

TL;DR: The most important prognostic variables for patients with osteosarcoma of the extremity was tumor necrosis evident following preoperative chemotherapy, and there is no consensus as to any prognostic variable that might be used to stratify patients before the onset of therapy.

TL;DR: The results of the present study suggest that the risk of local recurrence after curettage with a high-speed burr and reconstruction with autogenous graft with or without allograft bone is similar to that observed after use of cement and other adjuvant treatment.

TL;DR: In this paper, the authors considered whether a positive margin occurring after resection of a soft-tissue sarcoma of a limb would affect the incidence of local recurrence, and they found that patients with low-grade liposarcomas were expected to be a low-risk group as were those who had positive margins planned before surgery to preserve critical structures.

TL;DR: This series highlights the overall problem of distant failure in soft tissue sarcoma and reaffirms the importance of obtaining local control both in the head and neck, where uncontrolled local disease is the major cause of death, and in general since local relapse appears to increase the risk of distantFailure.