R
Robert Wattiaux
Researcher at Université de Namur
Publications - 103
Citations - 3310
Robert Wattiaux is an academic researcher from Université de Namur. The author has contributed to research in topics: Differential centrifugation & Lysosome. The author has an hindex of 26, co-authored 103 publications receiving 3211 citations.
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Journal ArticleDOI
Identification of HE1 as the Second Gene of Niemann-Pick C Disease
Saule Naureckiene,David E. Sleat,David E. Sleat,Henry Lackland,Anthony H. Fensom,Marie T. Vanier,Robert Wattiaux,Michel Jadot,Peter Lobel,Peter Lobel +9 more
TL;DR: Treatment of NP-C2 fibroblasts with exogenous recombinant HE1 protein ameliorated lysosomal accumulation of low density lipoprotein-derived cholesterol.
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Isolation of rat liver lysosomes by isopycnic centrifugation in a metrizamide gradient.
TL;DR: In this article, a procedure was devised to purify lysosomes from several grams of liver by centrifugation of an L fraction in a discontinuous metrizamide gradient.
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Endosomes, lysosomes: their implication in gene transfer.
TL;DR: Different factors that could affect the trafficking of plasmid DNA and influence transfection efficiency are considered.
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Intralysosomal hydrolysis of glycyl-l-phenylalanine 2-naphthylamide
TL;DR: Evidence is presented that Gly-L-Phe-2-NNap can possibly cause a disruption of the lysosomes as a result of its hydrolysis inside these organelles, and the usefulness of this enzyme and related dipeptidyl naphthylamides in lysOSomal-membrane-permeability studies is emphasized.
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Expression of Lamp-1 and Lamp-2 and their interactions with galectin-3 in human tumor cells
V. Sarafian,Michel Jadot,Jean-Michel Foidart,Jean-Jacques Letesson,F. Van Den Brule,Vincenzo Castronovo,Robert Wattiaux,Simone Wattiaux-De Coninck +7 more
TL;DR: The results support the idea that Lamps may be considered a new family of adhesive glycoproteins participating in the complex process of tumor invasion and metastasis.