R
Roberto Montesano
Researcher at University of Geneva
Publications - 143
Citations - 19595
Roberto Montesano is an academic researcher from University of Geneva. The author has contributed to research in topics: Angiogenesis & Endothelial stem cell. The author has an hindex of 66, co-authored 143 publications receiving 19252 citations. Previous affiliations of Roberto Montesano include Carnegie Mellon University & American Red Cross.
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Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
TL;DR: The results demonstrate that HGF, a polypeptide that was identified as a mitogen for cultured hepatocytes, has the properties of a paracrine mediator of epithelial morphogenesis, and suggest that it may play important roles in the formation of parenchymal organs during embryonic development.
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Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis
Stefano J. Mandriota,Lotta Jussila,Michael Jeltsch,Amelia Compagni,Danielle Baetens,Remko Prevo,Suneale Banerji,Joachim Huarte,Roberto Montesano,David A. Jackson,Lelio Orci,Kari Alitalo,Gerhard Christofori,Michael S. Pepper +13 more
TL;DR: It is demonstrated that VEGF‐C‐induced lymphangiogenesis mediates tumour cell dissemination and the formation of lymph node metastases.
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Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
TL;DR: It is demonstrated that like bFGF, VEGF induces an angiogenic response via a direct effect on endothelial cells, and that by acting in concert, these two cytokines have a potent synergistic effect on the induction of angiogenesis in vitro.
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Basic fibroblast growth factor induces angiogenesis in vitro.
TL;DR: It is shown that highly purified basic pituitary FGF can induce capillary endothelial cells to invade a three-dimensional collagen matrix and to organize themselves to form characteristic tubules that resemble blood capillaries.
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The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
Theodore Fotsis,Youming Zhang,Michael S. Pepper,Herman Adlercreutz,Roberto Montesano,Peter P. Nawroth,Lothar Schweigerer +6 more
TL;DR: It is reported that 2-methoxyoestradiol, an endogenous oestrogen metabolite of previously unknown function, is a potent inhibitor of endothelial cell proliferation and migration as well as angiogenesis in vitro.