Robson Luiz Puntel

TL;DR: Results suggest that oxaloacetate, malate, succinate, and citrate are effective antioxidants against basal and iron or QA-induced TBARS production, while α-ketoglutarate stimulatesTBARS production.

TL;DR: The results of the study revealed that incubating the brain tissues in the presence of 25 μM Fe2+ caused a significant increase in the number of brain cells damaged, and this damage can be prevented by food rich in antioxidants such as fruit and vegetables.

TL;DR: It is demonstrated that the plant extracts could protect against oxidative damage induced by various pro-oxidant agents that induce lipid peroxidation by different process, which indicates that M. officinalis could be considered an effective agent in the prevention of various neurological diseases associated with oxidative stress.

TL;DR: This review focuses on the requirement for Mn in human health as well as the diseases associated with excessive exposure to this metal, which has a paradoxal effect in animals, a Janus-faced metal.

TL;DR: It is suggested that antioxidant properties of citrate, malate and oxaloacetate were due to their ability to cancel iron redox activity by forming inactive complexes, whereas alpha-ketoglutarate and malonate pro-oxidant activity can be due to formation of active complexes with iron.