R
Rod Balhorn
Researcher at Lawrence Livermore National Laboratory
Publications - 104
Citations - 6863
Rod Balhorn is an academic researcher from Lawrence Livermore National Laboratory. The author has contributed to research in topics: Protamine & Sperm. The author has an hindex of 44, co-authored 104 publications receiving 6585 citations.
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Journal ArticleDOI
The protamine family of sperm nuclear proteins
TL;DR: Comparison of protamine gene and amino-acid sequences suggests that the family evolved from specialized histones through protamine-like proteins to the true protamines.
Journal ArticleDOI
Sequence-specific packaging of DNA in human sperm chromatin
TL;DR: The existence of sequence-specific nucleohistone and nucleoprotamine components within the human spermatozoon was demonstrated by cloning size-selected single-copy sequences and by using the derived clones as probes of nucleohistsone DNA and nucleobrotamine DNA.
Journal ArticleDOI
Processive translocation and DNA unwinding by individual RecBCD enzyme molecules
Piero R. Bianco,Laurence R. Brewer,Michele Corzett,Rod Balhorn,Yin Yeh,Stephen C. Kowalczykowski,Ronald J. Baskin +6 more
TL;DR: It is shown that unwinding is both continuous and processive, occurring at a maximum rate of 972 ± 172 base pairs per second, with as many as 42,300 base pairs of dsDNA unwound by a single RecBCD enzyme molecule.
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Aberrant protamine 1/protamine 2 ratios in sperm of infertile human males
TL;DR: The distribution of protamines in sperm obtained from a select group of infertile males producing an elevated level of large sperm heads, in contrast, was different from that of the fertile males.
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Protamine-Induced Condensation and Decondensation of the Same DNA Molecule
TL;DR: Condensation and decondensation experiments with lambda-phage DNA show that toroid formation and stability are influenced by the number of arginine-rich anchoring domains in protamine, and suggest that these proteins must be actively removed from sperm chromatin after fertilization.