Rodrigo M. Cordeiro

TL;DR: Simulations showed that molecular oxygen (O2) accumulated at the membrane interior and there were intermittent interruptions in the H-bond network around the HO radicals at the headgroups region, implying a large shift in the acid-base equilibrium between HO2 and O2(-).

TL;DR: Processes depending on direct contact between photosensitizers and lipids were revealed to be essential for the progress of lipid oxidation and consequently for aldehyde formation, providing a molecular-level explanation of why membrane binding correlates so well with the cell-killing efficiency of photosenitizers.

TL;DR: In this paper, anisotropic refractive index measurements by means of waveguide prism coupling and reflectometry as well as polarized infrared spectroscopy were used to analyze the polymer chain orientation in the films of conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV), prepared from polymer samples whose weight-average molecular weight (Mw) was varied in the broad range of 10−1600 kg/mol.

TL;DR: Simulation results may improve the understanding of redox signaling mechanisms and help in the interpretation of protein oxidative labeling experiments.