Roland Benz

TL;DR: Two different effects of cyanide on the Cl(-)-carrier system are suggested: in the micromolar concentration range cyanide reduced predominantly the translocation of the free carrier by inhibition of ATP synthesis by oxidative phosphorylation, whereas in the millimolar concentrationrange cyanide apparently inhibits the translocations rates of both the free and charged carriers by its binding to the carrier.

TL;DR: It is discussed whether the patient's bioptic specimen contained another human porin, which has not been studied to date in its natural environment, and whether the channel observed under these conditions had a single-channel conductance and was cation selective.

TL;DR: It is demonstrated that the water-soluble porins regained channel forming activity when the protein was preincubated with different sterols in the presence of a detergent.

TL;DR: This chapter describes the relaxation techniques and noise analysis of ion carriers in planar bilayers and analysis of current noise represents an alternative method for evaluating the rate constants of a carrier system.

TL;DR: CPE formed ion-permeable channels in artificial lipid bilayer membranes with a single-channel conductance was not a linear function of the bulk aqueous salt concentration indicating that point-negative charges at the CPE channel controlled ion transport, which resulted in the high cation selectivity of the Cpe channels, which suggested that anions are presumably not permeable through the C PE channels.