Roland Benz

TL;DR: It is shown that the post-translational mycoloylation of PorA occurs at Ser-15 and is necessary for the pore-forming activity of C. glutamicum.

TL;DR: Because of the high conductance of the membrane during breakdown it seems very likely that this results in pore formation, and it is probable that the reversible electrical breakdown is mainly caused by mechanical instability produced by electrostriction of the membranes, but the decrease in the Born energy for ion injection into the membrane, accompanying the decreases in membrane thickness, may play also an important role.

TL;DR: It is discussed that the superior therapeutic effect of salmon Ct as a tool to treat bone disorders, including Paget disease, osteoporosis, and hypercalcemia of malignancy, rather than human Ct is related to the lack of the fibrillating property of salmonCt.

TL;DR: The data suggest that the two hly paralogues encode identical toxin functions; however, due to different regulation of expression, they participate at distinct stages of the infectious process.

TL;DR: The pore-forming activity of the major outer-membrane protein FomA of the anaerobic Fusobacterium nucleatum was studied in artificial lipid bilayer membranes and strongly suggests that the trimer is the functional unit of the porin.