Roland Benz

TL;DR: Pxmp2 is the first peroxisomal channel identified, and its existence leads to prediction that the mammalian peroxISomal membrane is permeable to small solutes while transfer of “bulky” metabolites, e.g., cofactors (NAD/H, NADP/ H, and CoA) and ATP, requires specific transporters.

TL;DR: It is shown that under favorable circumstances the equilibrium constant of complex formation in the aqueous phase may be obtained from membrane experiments that allow a quantitative determination of rate constants describing carrier-mediated ion transport.

TL;DR: Patch-clamp analyses indicate that PorB channel activity is tightly regulated in intact epithelial cells, which provide important mechanistic clues on the intracellular pathogen accommodation reminiscent of mitochondrial endosymbiosis.

TL;DR: The incorporation of porins into artificial lipid bilayer membranes showed that they are able to form pores with approximately the same specific activity and the number of gating charges varies, however, for pores from different tissues, indicating a different sensitivity to the potential as a result of a possible different function.

TL;DR: A modified version of the charge-pulse relaxation technique with improved time resolution was applied to the study of transport kinetics of hydrophobic ions through lipid bilayer membranes, and the results support the model proposed earlier.