R
Róli Rodrigues Simões
Researcher at Universidade Federal de Santa Catarina
Publications - 11
Citations - 367
Róli Rodrigues Simões is an academic researcher from Universidade Federal de Santa Catarina. The author has contributed to research in topics: TRPV1 & TRPM8. The author has an hindex of 5, co-authored 10 publications receiving 319 citations. Previous affiliations of Róli Rodrigues Simões include Universidade Federal de Santa Maria.
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Journal ArticleDOI
Acute effects of glyphosate herbicide on metabolic and enzymatic parameters of silver catfish (Rhamdia quelen).
Lissandra Glusczak,Denise dos Santos Miron,Bibiana Silveira Moraes,Róli Rodrigues Simões,Maria Rosa Chitolina Schetinger,Vera Maria Morsch,Vânia Lúcia Loro +6 more
TL;DR: The present results showed that in 96 h, glyphosate changed AChE activity, metabolic parameters and TBARS production, which can be used as herbicide toxicity indicators considering environmentally relevant concentration.
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Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K+ Channel/p38-MAPK Signalling Pathway.
Laís Mara Siqueira das Neves,Elaine C. D. Gonçalves,Juliana Cavalli,Graziela Vieira,Larissa R. Laurindo,Róli Rodrigues Simões,Igor dos Santos Coelho,Adair R.S. Santos,Alexandre Marcio Marcolino,Maíra Cola,Rafael C. Dutra +10 more
TL;DR: Analysis of signalling pathway downstream of cannabinoid receptors activation reveals that anti-inflammatory effects of PBM depend, in great extent, on its ability to activate ATP-dependent K+ channels and p38 mitogen-activated protein kinase.
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Oral treatment with essential oil of Hyptis spicigera Lam. (Lamiaceae) reduces acute pain and inflammation in mice: Potential interactions with transient receptor potential (TRP) ion channels.
Róli Rodrigues Simões,Igor dos Santos Coelho,Stella C. Junqueira,Glauce Regina Pigatto,Marcos José Salvador,Adair R.S. Santos,Felipe Meira de Faria +6 more
TL;DR: This study demonstrated the efficacy of EOHs on experimental models of nociception and found the involvement of TRP channels V1, A1 and M8 with Eohs activity, which was remarkably potent and efficient in inhibiting pain evoked by menthol, a TRPM8 channel activator.
Journal ArticleDOI
Bradykinin Receptors Play a Critical Role in the Chronic Post-ischaemia Pain Model
Elaine C. D. Gonçalves,Graziela Vieira,Tainara R. Gonçalves,Róli Rodrigues Simões,Indiara Brusco,Sara Marchesan Oliveira,João B. Calixto,Maíra Cola,Adair R.S. Santos,Rafael C. Dutra +9 more
TL;DR: The participation of BKRs in the development and maintenance of chronic pain associated with the CPIP model, possibly linking them to CRPS-I pathogenesis is suggested.
Journal ArticleDOI
Oral treatment with methanolic extract of the root bark of Condalia buxifolia Reissek alleviates acute pain and inflammation in mice: Potential interactions with PGE2, TRPV1/ASIC and PKA signaling pathways.
Róli Rodrigues Simões,Igor dos Santos Coelho,Caroline Cunha do Espírito Santo,Ademir F. Morel,Eliane Maria Zanchet,Adair R.S. Santos,Adair R.S. Santos +6 more
TL;DR: Findings provide new evidence indicating that Condalia buxifolia reduces the acute painful behavior of animals caused by chemical stimuli and suggest involvement of PGE2, TRPV1/ASIC and PKA signaling pathways, and require integrity of the capsaicin-sensitive central C-fiber afferents.