Showing papers in "Journal of Ethnopharmacology in 2017"

TL;DR: Modern pharmacological studies have now proven many traditional uses of P. oleracea, including anti- hyperglycemic and anti-hyperlipidemic, renoprotective and hepatoprot protective effects.

TL;DR: This review aims to provide up-to-date information on the botanical characterization, medicinal uses, chemical constituents, pharmacological activities, and toxicity of B. striata and the possible exploitation of this plant for the treatment of different diseases, and uncovers opportunities for future research.

TL;DR: The findings of the studied reports in this review article represent therapeutic characteristics of Achillea species and account for their significant impact on the current and future modern medicine.

TL;DR: This study aimed to identify and document species of medicinal plants used by local experts from riverine communities in the North Araguaia microregion in Mato Grosso State, and to further chemical and pharmacological studies on species selected based on searches in the relevant literature.

TL;DR: MFP50 and MFP90 have markedly antihyperglycemic and antihyperlipidemic effects and can clearly relieve diabetes symptoms in the T2DM rat model, suggesting M. alba fruit polysaccharides may potentially be utilized as an effective treatment for T2 DM.

TL;DR: Despite the richness which characterizes Tafilalet regarding diversity and effectiveness of medicinal plants as well as the largest culture and knowledge related to the popular phytotherapy among local people in this region, several procedures must be realized to protect and to valorize this interesting inheritance.

TL;DR: The successful inclusion of Rehmanniae Radix in clinical trials and preclinical studies for the management of osteoporosis has attracted rising attentions for identifying potential anti-osteoporotic candidates from this plant and clinical existing TCM formulas, which will further speed up anti-stochastic drug discovery processes.

TL;DR: Overall, the available evidence suggests that GbE has potentially beneficial effects over placebo on cognitive performance, activities of daily living, and clinical global impression in the treatment of dementia at doses greater than 200mg/day (usually 240mg/ day) administrated for 22 weeks or longer, and that Ginkgo biloba extract appears to be safe for human consumption.

TL;DR: Multidisciplinary studies have emerged as a strong support for antimicrobial investigations and show the importance of including toxicity when studying antimicrobial efficacy.

TL;DR: This study showed the importance of folk medicine in the healthcare system for the local people living in the study area and represents a useful documentation, which can contribute to preserving knowledge on the use of medicinal plants in this region.

TL;DR: Scientific validation and the documentation of Ayurvedic drugs are very essential for its quality evaluation and global acceptance.

TL;DR: The mechanism of antiproliferative/cytotoxic effects of the tested compounds was investigated and it was found that only 5 induced significant cell cycle arrest at G0/G1-phase which is indicative of its antiprolifierative properties.

TL;DR: Using of the methods of rational preparation, reasonable compatibility, and proper processing based on traditional experiences and new technologies, can enable Aconitum to be used safely and effectively.

TL;DR: This review presents extensive information about the medicinal plants possessing antibacterial activity that has been scientifically studied and are popularly used in Mexico, including a list with the top plant species with antibacterial activities in vitro.

TL;DR: This review summarizes the pre-clinical and clinical evidence on the benefits of TCM and their active ingredients, and provides a comprehensive information and reliable basis for the exploration of new treatment strategies of botanical drugs in the therapy of PF.

TL;DR: Data suggested that the main bioactives in GLPs was F31, which was determined to be a β-heteropolysaccharide with the weight-average molecular weight of 15.9kDa, which strongly suggest that F31 has antidiabetic potential.

TL;DR: The n-hexanic and the ethanolic extracts from Calendula flowers influence the inflammatory phase by activating the transcription factor NF-κB and by increasing the amount of the chemokine IL-8 in human immortalized keratinocytes.

TL;DR: This review aims to provide an overview of the compatibility rationality of TCM from the perspective of pharmaceutics, pharmacokinetics, and/or pharmacodynamics, and could be served as an informative reference for researchers interested in compound prescriptions and holistic therapies.

TL;DR: A network pharmacology-based method, which combined large-scale text-mining, drug-likeness filtering, target prediction and network analysis to decipher the mechanisms of action for the most widely studied medicinal herbs in AD treatment is proposed.

TL;DR: This work successfully predict, illuminate and confirm the molecular synergy of YHD for HER2-positive breast cancer and found the potential Her2- positive breast cancer associated targets, cluster, biological processes and pathways.

TL;DR: There is a need for deeper investigation in the mechanisms of higenamine action, as well as well-designed preclinical and clinical trials studies to test the safety and clinical value of the drug.

TL;DR: There is some evidence for extracts' pharmacological effects on Alzheimer's and Parkinson's diseases, cancer, diabetes, hypertension, and drug interaction with standard-of-care medications.

TL;DR: This review aims to provide systematically reorganized information on distributions, botanical characteristics, ethnopharmacology, chemical constituents, qualitative and quantitative analysis, pharmacological activities, and toxicity of Achyranthes species to support their therapeutic potential.

TL;DR: Curcumin can induce pharmacokinetic alterations such as changes in Cmax and AUC when concomitantly used with pharmacological agents like cardiovascular drugs, antidepressants, anticoagulants, antibiotics, chemotherapeutic agents, and antihistamines.

TL;DR: Leaves of M. speciosa (kratom) had the most common documented ethnomedicinal uses as an opium substitute or remedy for addiction and other species of Mitragyna were reportedly used for treating pain, however the mode of preparation was most often cited as topical application.

TL;DR: It was found that the Ayurvedic Pharmacopoeia of India has its development during 20th Century as an official document of Govt.

TL;DR: It is suggested that Anoectochilus roxburghii polysaccharide possessed hepatoprotective effect against CCl4-induced hepatotoxicity in mice and the action might in part be through reducing oxidative stress, inflammation and apoptosis.

TL;DR: It is suggested that imperatorin is an effective inhibitor of HIF-1 and provide new perspectives into the mechanism of its anticancer activity.

TL;DR: Hypoglycemic, anti-hyperglycemic and anti-diabetic activities of some dietary fruits, vegetables, beverages, oils and spices and their active hypoglycemic constituents are covered to improve management of type 2 diabetes.

TL;DR: Bacopa inhibits the release of inflammatory cytokines from microglial cells and inhibits enzymes associated with inflammation in the brain, and offers a promising source of novel therapeutics for the treatment of many CNS disorders.