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Rosemarie Hunziker
Researcher at National Institutes of Health
Publications - 13
Citations - 874
Rosemarie Hunziker is an academic researcher from National Institutes of Health. The author has contributed to research in topics: MHC class I & Interleukin 21. The author has an hindex of 9, co-authored 13 publications receiving 856 citations. Previous affiliations of Rosemarie Hunziker include National Institute of Standards and Technology.
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Journal ArticleDOI
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
Matthew R. Young,Jian Jian Li,Jian Jian Li,Mercedes Rincon,Richard A. Flavell,B. K. Sathyanarayana,Rosemarie Hunziker,Rosemarie Hunziker,Nancy H. Colburn +8 more
TL;DR: It is concluded that transactivation of a subset of AP-1-dependent genes is required for tumor promotion and may be targeted for cancer prevention.
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A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development.
Leslie B. King,Melanie S. Vacchio,Katherine Dixon,Rosemarie Hunziker,David H. Margulies,Jonathan D. Ashwell +5 more
TL;DR: It is suggested that glucocorticoids are necessary for survival and maturation of thymocytes, and are consistent with a role for steroids in both the transition from CD4-CD8- to CD4+CD8+ cells and the survival of CD4–CD8– cells stimulated via the TCR.
Journal Article
Host MHC class I molecules modulate in vivo expression of a NK cell receptor.
TL;DR: In this paper, the influence of specific host MHC class I molecules on Ly-49 expression was determined and it was shown that Dd itself is sufficient for this effect and suggest that Ly49 engages Dd-alpha 1/alpha 2 domains.
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A family of murine NK cell receptors specific for target cell MHC class I molecules.
Wayne M. Yokoyama,Brian F. Daniels,William E. Seaman,Rosemarie Hunziker,David H. Margulies,Hamish R. C. Smith +5 more
TL;DR: Findings highlight the emerging significance of the Ly-49 family in NK cell activity and suggest it may be related to human molecules that are selectively expressed on NK cells and influence NK cell specificity.
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Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology:
TL;DR: MPS research has made notable progress in the past three years in both cell sourcing and characterization, and academic and commercial players in the MPS community are demonstrating their ability to meet the translational challenges required to apply MPS technologies to accelerate drug development and advance toxicology.