Matthew R. Young

TL;DR: Results indicate arsenic can act as a carcinogen by inducing DNA hypomethylation, which in turn facilitates aberrant gene expression, and they constitute a tenable theory of mechanism in arsenic carcinogenesis.

TL;DR: It is concluded that transactivation of a subset of AP-1-dependent genes is required for tumor promotion and may be targeted for cancer prevention.

TL;DR: A rapidly activatable, cancer-selective fluorescence imaging probe that fluoresces upon cleavage by a cancer-specific enzyme and can be used during surgical or endoscopic tumor removal procedures, and several other aminopeptidase–based reagents identified by the authors could help surgeons to track down tiny tumors dispersed throughout body cavities.

TL;DR: The role of AMPK in regulating inflammation, metabolism, and other regulatory processes with an emphasis on cancer is reviewed and the potential for targeting AMPK to treat various types of cancer is discussed.

TL;DR: It is demonstrated that AP-1 and NF-κB are both required for maintaining the transformed phenotypes where inhibition of either activity suppresses transformation response in JB6 cells as well as human keratinocytes and transgenic mouse.