R
Roshan M. Kumar
Researcher at Massachusetts Institute of Technology
Publications - 25
Citations - 9792
Roshan M. Kumar is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Cellular differentiation & Regulation of gene expression. The author has an hindex of 14, co-authored 25 publications receiving 9300 citations. Previous affiliations of Roshan M. Kumar include Wyss Institute for Biologically Inspired Engineering & Harvard University.
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Journal ArticleDOI
Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells
TL;DR: In this paper, PcG proteins are found to occupy and repress transcription from an intronic region containing the microRNA miR-214 in undifferentiated skeletal muscle cells (SMC).
Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells
TL;DR: In this article, PcG proteins are found to occupy and repress transcription from an intronic region containing the microRNA miR-214 in undifferentiated skeletal muscle cells (SMC).
Journal ArticleDOI
Global and gene‐specific analyses show distinct roles for Myod and Myog at a common set of promoters
Yi Cao,Roshan M. Kumar,Bennett H. Penn,Charlotte A. Berkes,Charles Kooperberg,Laurie A. Boyer,Richard A. Young,Richard A. Young,Stephen J. Tapscott +8 more
TL;DR: The role of Myog in mediating terminal differentiation is, in part, to enhance expression of a subset of genes previously initiated by Myod.
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Parenting and survival in anthropoid primates: Caretakers live longer
TL;DR: It is predicted that females tend to live longer than males in the species where the mother does most or all of the care of offspring, that there is no difference in survival between the sexes in species in which both parents participate about equally in infant care, and that in thespecies where the father does a greater amount of care than the mother, males tend toLive longer.
Journal ArticleDOI
The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during Development
Jingqiang Wang,Roshan M. Kumar,Vanessa J. Biggs,Hansol Lee,Yun Chen,Michael H. Kagey,Richard A. Young,Cory Abate-Shen,Cory Abate-Shen +8 more
TL;DR: It is shown that transcriptional repression by the Msx1 homeoprotein in myoblast cells requires the recruitment of Polycomb to target genes located at the nuclear periphery.