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Ruggero Dondi

Researcher at University of Bath

Publications -  17
Citations -  496

Ruggero Dondi is an academic researcher from University of Bath. The author has contributed to research in topics: Photodynamic therapy & Silver nanoparticle. The author has an hindex of 10, co-authored 16 publications receiving 426 citations. Previous affiliations of Ruggero Dondi include Merck Serono & University of California, Los Angeles.

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Journal ArticleDOI

Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.

TL;DR: The reversibility of QM reaction can now be predictably adjusted for any desired application after it was demonstrated that a dC N3-QM adduct is made stable over the course of observation by the presence of an electron-withdrawing ester group that inhibits QM regeneration.
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Enhanced paracellular transport of insulin can be achieved via transient induction of myosin light chain phosphorylation.

TL;DR: In this paper, two stable Permeant Inhibitor of Phosphatase (PIP) peptides were rationally designed to stimulate phosphorylation of intracellular epithelial myosin light chain (MLC) and screened using Caco-2 monolayers in vitro.
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Highly size and shape-controlled synthesis of silver nanoparticles via a templated tollens reaction

TL;DR: A mild, facile one-step synthetic strategy for the preparation of size-and shape-controlled silver nanoparticles (AgNPs) by the use of triazole sugar ligands scaffolded by a central resorcinol ether core is presented.
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Endolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines.

TL;DR: It is demonstrated that chlorin e6 can be repurposed for PCI by conjugating the chlorin to a cell penetrating peptide, using bioorthogonal ligation chemistry, which enables targeting of endosomal membranes so that light-triggered cytosolic release of an entrapped nano-sized cytotoxin can be achieved with consequent improvement in cytotoxicity.