R
Ryan D. Nipp
Researcher at Harvard University
Publications - 204
Citations - 4555
Ryan D. Nipp is an academic researcher from Harvard University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 26, co-authored 171 publications receiving 2561 citations. Previous affiliations of Ryan D. Nipp include Durham University & Texas Tech University Health Sciences Center.
Papers
More filters
Journal ArticleDOI
Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.
Janet E. Murphy,Jennifer Y. Wo,David P. Ryan,Jeffrey W. Clark,Wenqing Jiang,Beow Y. Yeap,Lorraine C. Drapek,Leilana Ly,Christian V. Baglini,Lawrence S. Blaszkowsky,Cristina R. Ferrone,Aparna Raj Parikh,Colin D. Weekes,Ryan D. Nipp,Eunice L. Kwak,Jill N. Allen,Ryan B. Corcoran,David T. Ting,Jason E. Faris,Andrew X. Zhu,Lipika Goyal,David H. Berger,Motaz Qadan,Keith D. Lillemoe,Nilesh Talele,Rakesh K. Jain,Thomas F. DeLaney,Dan G. Duda,Yves Boucher,Carlos Fernandez-del Castillo,Theodore S. Hong +30 more
TL;DR: Total neoadjuvant therapy with FOLFIRINOX, losartan, and chemoradiotherapy provides downstaging of locally advanced pancreatic ductal adenocarcinoma and is associated with an R0 resection rate of 61%.
Journal ArticleDOI
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers.
Aparna Raj Parikh,Ignaty Leshchiner,Liudmila Elagina,Lipika Goyal,Chaya Levovitz,Giulia Siravegna,Dimitri Livitz,Kahn Rhrissorrakrai,Elizabeth E. Martin,Emily E. Van Seventer,Megan Hanna,Kara Slowik,Filippo Utro,Christopher J. Pinto,Alicia Wong,Brian P. Danysh,Ferran Fece de la Cruz,Isobel J Fetter,Brandon Nadres,Heather A. Shahzade,Jill N. Allen,Lawrence S. Blaszkowsky,Jeffrey W. Clark,Bruce J. Giantonio,Janet E. Murphy,Ryan D. Nipp,Eric Roeland,David P. Ryan,Colin D. Weekes,Eunice L. Kwak,Jason E. Faris,Jennifer Y. Wo,François Aguet,Ipsita Dey-Guha,Mehlika Hazar-Rethinam,Dora Dias-Santagata,David T. Ting,Andrew X. Zhu,Theodore S. Hong,Todd R. Golub,Todd R. Golub,Todd R. Golub,A. John Iafrate,Viktor A. Adalsteinsson,Alberto Bardelli,Laxmi Parida,Dejan Juric,Gad Getz,Ryan B. Corcoran +48 more
TL;DR: Direct prospective comparison of circulating tumor DNA and tissue biopsy sequencing shows the superiority of liquid biopsies for capturing clinically relevant alterations mediating resistance to targeted therapies in cancer patients.
Journal ArticleDOI
Predictors of Resectability and Survival in Patients With Borderline and Locally Advanced Pancreatic Cancer who Underwent Neoadjuvant Treatment With FOLFIRINOX.
Theodoros Michelakos,Ilaria Pergolini,Carlos Fernandez-del Castillo,Kim C. Honselmann,Lei Cai,Vikram Deshpande,Jennifer Y. Wo,David P. Ryan,Jill N. Allen,Lawrence S. Blaszkowsky,Jeffrey W. Clark,Janet E. Murphy,Ryan D. Nipp,Aparna Raj Parikh,Motaz Qadan,Andrew L. Warshaw,Theodore S. Hong,Keith D. Lillemoe,Cristina R. Ferrone +18 more
TL;DR: Whether preoperative factors can predict resectability of borderline resectable and locally advanced pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX and which patients might benefit from adjuvant therapy is investigated.
Journal ArticleDOI
The relationship between coping strategies, quality of life, and mood in patients with incurable cancer.
Ryan D. Nipp,Areej El-Jawahri,Joel N. Fishbein,Justin Eusebio,Jamie M. Stagl,Emily R. Gallagher,Elyse R. Park,Vicki A. Jackson,William F. Pirl,Joseph A. Greer,Jennifer S. Temel +10 more
TL;DR: Patients with incurable cancer face many physical and emotional stressors, yet little is known about their coping strategies or the relationship between their cope strategies, quality of life (QOL), and mood.
Journal ArticleDOI
Coping and Prognostic Awareness in Patients With Advanced Cancer
Ryan D. Nipp,Joseph A. Greer,Areej El-Jawahri,Samantha M.C. Moran,Lara Traeger,Jamie M. Jacobs,Juliet Jacobsen,Emily R. Gallagher,Elyse R. Park,David P. Ryan,Vicki A. Jackson,William F. Pirl,Jennifer S. Temel +12 more
TL;DR: Prognostic awareness is related to worse QOL and mood in patients with newly diagnosed, incurable cancer; however, the use of certain coping strategies may buffer these relationships.