K
Kahn Rhrissorrakrai
Researcher at IBM
Publications - 59
Citations - 2267
Kahn Rhrissorrakrai is an academic researcher from IBM. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 14, co-authored 44 publications receiving 1846 citations. Previous affiliations of Kahn Rhrissorrakrai include National Institutes of Health & Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
Mark Gerstein,Zhi John Lu,Eric L. Van Nostrand,Chao Cheng,Bradley I. Arshinoff,Tao Liu,Kevin Y. Yip,R. Robilotto,Andreas Rechtsteiner,Kohta Ikegami,P. Alves,A. Chateigner,Marc D. Perry,Mitzi Morris,Raymond K. Auerbach,X. Feng,Jing Leng,A. Vielle,Wei Niu,Kahn Rhrissorrakrai,Ashish Agarwal,Roger P. Alexander,Galt P. Barber,Cathleen M. Brdlik,J. Brennan,Jeremy Brouillet,Adrian Carr,Ming Sin Cheung,Hiram Clawson,Sergio Contrino,Luke Dannenberg,Abby F. Dernburg,Arshad Desai,L. Dick,Andréa C. Dosé,Jiang Du,Thea A. Egelhofer,Sevinc Ercan,Ghia Euskirchen,Brent Ewing,Elise A. Feingold,Reto Gassmann,Peter J. Good,Philip Green,Francois Gullier,M. Gutwein,Mark S. Guyer,Lukas Habegger,Ting Han,Jorja G. Henikoff,Stefan R. Henz,Angie S. Hinrichs,H. Holster,Tony Hyman,A. Leo Iniguez,J. Janette,M. Jensen,Masaomi Kato,W. James Kent,E. Kephart,Vishal Khivansara,Ekta Khurana,John Kim,P. Kolasinska-Zwierz,Eric C. Lai,Isabel J. Latorre,Amber Leahey,Suzanna E. Lewis,Paul Lloyd,Lucas Lochovsky,Rebecca F. Lowdon,Yaniv Lubling,Rachel Lyne,Michael J. MacCoss,Sebastian D. Mackowiak,Marco Mangone,Sheldon J. McKay,D. Mecenas,Gennifer E. Merrihew,David M. Miller,A. Muroyama,John I. Murray,Siew Loon Ooi,Hoang Pham,T. Phippen,Elicia Preston,Nikolaus Rajewsky,Gunnar Rätsch,Heidi Rosenbaum,Joel Rozowsky,Kim Rutherford,P. Ruzanov,Mihail Sarov,Rajkumar Sasidharan,Andrea Sboner,P. Scheid,Eran Segal,Hyunjin Shin,C. Shou,Frank J. Slack,C. Slightam,Richard J.H. Smith,William C. Spencer,Eo Stinson,S. Taing,Teruaki Takasaki,D. Vafeados,Ksenia Voronina,Guilin Wang,Nicole L. Washington,Christina M. Whittle,Beijing Wu,Koon-Kiu Yan,Georg Zeller,Z. Zha,Mei Zhong,Xingliang Zhou,Julie Ahringer,Susan Strome,Kristin C. Gunsalus,Gos Micklem,X. Shirley Liu,Valerie Reinke,Stuart K. Kim,LaDeana W. Hillier,Steven Henikoff,Fabio Piano,Michael Snyder,Lincoln Stein,Jason D. Lieb,Robert H. Waterston +130 more
TL;DR: These studies identified regions of the nematode and fly genomes that show highly occupied targets (or HOT) regions where DNA was bound by more than 15 of the transcription factors analyzed and the expression of related genes were characterized, providing insights into the organization, structure, and function of the two genomes.
Journal ArticleDOI
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers.
Aparna Raj Parikh,Ignaty Leshchiner,Liudmila Elagina,Lipika Goyal,Chaya Levovitz,Giulia Siravegna,Dimitri Livitz,Kahn Rhrissorrakrai,Elizabeth E. Martin,Emily E. Van Seventer,Megan Hanna,Kara Slowik,Filippo Utro,Christopher J. Pinto,Alicia Wong,Brian P. Danysh,Ferran Fece de la Cruz,Isobel J Fetter,Brandon Nadres,Heather A. Shahzade,Jill N. Allen,Lawrence S. Blaszkowsky,Jeffrey W. Clark,Bruce J. Giantonio,Janet E. Murphy,Ryan D. Nipp,Eric Roeland,David P. Ryan,Colin D. Weekes,Eunice L. Kwak,Jason E. Faris,Jennifer Y. Wo,François Aguet,Ipsita Dey-Guha,Mehlika Hazar-Rethinam,Dora Dias-Santagata,David T. Ting,Andrew X. Zhu,Theodore S. Hong,Todd R. Golub,Todd R. Golub,Todd R. Golub,A. John Iafrate,Viktor A. Adalsteinsson,Alberto Bardelli,Laxmi Parida,Dejan Juric,Gad Getz,Ryan B. Corcoran +48 more
TL;DR: Direct prospective comparison of circulating tumor DNA and tissue biopsy sequencing shows the superiority of liquid biopsies for capturing clinically relevant alterations mediating resistance to targeted therapies in cancer patients.
Journal ArticleDOI
A protein domain-based interactome network for C. elegans early embryogenesis
Mike Boxem,Zoltan Maliga,Niels Klitgord,Na Li,Irma Lemmens,Miyeko D. Mana,Lorenzo de Lichtervelde,Joram D. Mul,Diederik van de Peut,Maxime Devos,Nicolas Simonis,Muhammed A. Yildirim,Murat Cokol,Huey Ling Kao,Anne Sophie de Smet,Haidong Wang,Anne-Lore Schlaitz,Tong Hao,Stuart Milstein,Changyu Fan,Mike Tipsword,Kevin Drew,Matilde Galli,Kahn Rhrissorrakrai,David N. Drechsel,Daphne Koller,Frederick P. Roth,Lilia M. Iakoucheva,A. Keith Dunker,Richard Bonneau,Kristin C. Gunsalus,David E. Hill,Fabio Piano,Jan Tavernier,Sander van den Heuvel,Anthony A. Hyman,Marc Vidal +36 more
TL;DR: An experimental strategy to efficiently identify interaction domains was developed and a domain-based interactome network for proteins involved in C. elegans early-embryonic cell divisions was generated, resulting in a more complete interactionome network.
Journal ArticleDOI
MINE: Module Identification in Networks
TL;DR: An agglomerative clustering method that is able to identify highly modular sets of gene products within highly interconnected molecular interaction networks and obtains good overall recall and precision of functional annotations in protein-protein interaction networks from both S. cerevisiae and C. elegans.
Journal ArticleDOI
Mating induces an immune response and developmental switch in the Drosophila oviduct
Anat Kapelnikov,Einat Zelinger,Yuval Gottlieb,Kahn Rhrissorrakrai,Kristin C. Gunsalus,Yael Heifetz +5 more
TL;DR: The combined results indicate that mating triggers molecular and biochemical changes that mediate progression from a “poised” state to a mature, functional stage.