R
Ryoji Kobayashi
Researcher at Kagawa University
Publications - 196
Citations - 4120
Ryoji Kobayashi is an academic researcher from Kagawa University. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 31, co-authored 195 publications receiving 3646 citations.
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Journal ArticleDOI
Pharmacology of protein kinase inhibitors.
Hiroyoshi Hidaka,Ryoji Kobayashi +1 more
Journal ArticleDOI
STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase
Hiroshi Tokumitsu,Hiroyuki Inuzuka,Yumi Ishikawa,Masahiko Ikeda,Ikutaro Saji,Ryoji Kobayashi +5 more
TL;DR: Results indicate that STO-609 is a selective and cell-permeable inhibitor of CaM-KK and that it may be a useful tool for evaluating the physiological significance of the CaM/calmodulin-dependent protein kinase kinase pathway in vivo as well as in vitro.
Journal ArticleDOI
Substrate recognition by the collagen-binding domain of Clostridium histolyticum class I collagenase.
TL;DR: Results suggested that the binding site(s) for the CBD is(are) present in the collagenous region and specifically recognizes the triple-helical conformation made by three polypeptide chains in thecollagenous region.
Journal ArticleDOI
A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans.
Yoshishige Kimura,Ethan E. Corcoran,Koh Eto,Keiko Gengyo-Ando,Masaaki Muramatsu,Ryoji Kobayashi,Jonathan H. Freedman,Shohei Mitani,Masatoshi Hagiwara,Anthony R. Means,Hiroshi Tokumitsu +10 more
TL;DR: It is reported that all components of this CaMK cascade are coexpressed in head neurons of Caenorhabditis elegans and regulates CRE‐mediated transcription in a subset of head neurons in living nematodes.
Journal ArticleDOI
Bone marrow-derived mesenchymal stem cells (JR-031) for steroid-refractory grade III or IV acute graft-versus-host disease: a phase II/III study
Kazuo Muroi,Koichi Miyamura,Masaya Okada,Takuya Yamashita,Makoto Murata,Takayuki Ishikawa,Naokuni Uike,Michihiro Hidaka,Ryoji Kobayashi,Masahiro Imamura,Junji Tanaka,Kazuteru Ohashi,Shuichi Taniguchi,Takashi Ikeda,Tetsuya Eto,Masaki Mori,Mariko Yamaoka,Keiya Ozawa +17 more
TL;DR: Two clinical trials suggest JR-031 to be effective for steroid-refractory aGVHD and survival was significantly better in patients showing overall response (OR; CR+PR) than in those showing no OR at 4 weeks.