R
Ryuta Kamekura
Researcher at Sapporo Medical University
Publications - 65
Citations - 1517
Ryuta Kamekura is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Tight junction & Barrier function. The author has an hindex of 20, co-authored 59 publications receiving 1224 citations. Previous affiliations of Ryuta Kamekura include Emory University & University of Michigan.
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Journal ArticleDOI
The role of IL‐33 and its receptor ST2 in human nasal epithelium with allergic rhinitis
TL;DR: The IL‐33 induces T helper 2‐type inflammatory responses and is considered to play a crucial rule in allergic inflammations, such as asthma and atopic dermatitis, but the role of IL‐ 33 and its receptor ST2 in allergic rhinitis remains unknown.
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Regulation of Tight Junctions in Upper Airway Epithelium
Takashi Kojima,Mitsuru Go,Kenichi Takano,Makoto Kurose,Tsuyoshi Ohkuni,Jun-ichi Koizumi,Ryuta Kamekura,Noriko Ogasawara,Tomoyuki Masaki,Jun Fuchimoto,Kazufumi Obata,Satoshi Hirakawa,Kazuaki Nomura,Takashi Keira,Ryou Miyata,Nobuhiro Fujii,Hiroyuki Tsutsumi,Tetsuo Himi,Norimasa Sawada +18 more
TL;DR: Recent progress in the understanding of the regulation of tight junctions in the upper airway epithelium under normal, allergic, and RSV-infected conditions is summarized.
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Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling
Ryuta Kamekura,Keli Kolegraff,Porfirio Nava,Roland Hilgarth,Mingli Feng,Charkes Parkos,Asma Nusrat +6 more
TL;DR: It is demonstrated that partner desmosomal cadherins Dsg2 and Dsc2 play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR signaling.
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Alteration of circulating type 2 follicular helper T cells and regulatory B cells underlies the comorbid association of allergic rhinitis with bronchial asthma.
Ryuta Kamekura,Katsunori Shigehara,Satsuki Miyajima,Sumito Jitsukawa,Koji Kawata,Keiji Yamashita,Tomonori Nagaya,Ayako Kumagai,Akinori Sato,Hiroshi Matsumiya,Noriko Ogasawara,Nobuhiko Seki,Kenichi Takano,Yasuo Kokai,Hiroki Takahashi,Tetsuo Himi,Shingo Ichimiya +16 more
TL;DR: Findings indicate that relative decrease in Breg cells under the condition of Tfh2 cell skewing is a putative exaggerating factor of AR to bronchial asthma.
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Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells
Ryuta Kamekura,Takashi Kojima,Jun-ichi Koizumi,Noriko Ogasawara,Makoto Kurose,Mitsuru Go,Atsushi Harimaya,Masaki Murata,Satoshi Tanaka,Hideki Chiba,Tetsuo Himi,Norimasa Sawada +11 more
TL;DR: The nasal-epithelial-derived TSLP thus not only activates DCs but also preserves the epithelial barrier via the upregulation of tight-junction proteins, thereby regulating antigen sensitization during the early stage of allergic rhinitis.