S
Sabine Heiland
Researcher at University Hospital Heidelberg
Publications - 27
Citations - 4656
Sabine Heiland is an academic researcher from University Hospital Heidelberg. The author has contributed to research in topics: Stroke & Ischemia. The author has an hindex of 22, co-authored 27 publications receiving 4223 citations. Previous affiliations of Sabine Heiland include Heidelberg University.
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Journal ArticleDOI
Brain tumour cells interconnect to a functional and resistant network
Matthias Osswald,Matthias Osswald,Erik Jung,Erik Jung,Felix Sahm,Felix Sahm,Gergely Solecki,Gergely Solecki,Varun Venkataramani,Jonas Blaes,Jonas Blaes,Sophie Weil,Sophie Weil,Heinz Horstmann,Benedikt Wiestler,Benedikt Wiestler,Benedikt Wiestler,Mustafa Syed,Mustafa Syed,Lulu Huang,Lulu Huang,Miriam Ratliff,Miriam Ratliff,Kianush Karimian Jazi,Kianush Karimian Jazi,Felix T. Kurz,Torsten Schmenger,Torsten Schmenger,Dieter Lemke,Dieter Lemke,Miriam Gömmel,Miriam Gömmel,Martin Pauli,Yunxiang Liao,Yunxiang Liao,Peter Häring,Stefan Pusch,Stefan Pusch,Verena Herl,Christian Steinhäuser,Damir Krunic,Mostafa Jarahian,Hrvoje Miletic,Anna S. Berghoff,Oliver Griesbeck,Georgios Kalamakis,Olga Garaschuk,Matthias Preusser,Samuel Weiss,Hai-Kun Liu,Sabine Heiland,Michael Platten,Michael Platten,Peter E. Huber,Peter E. Huber,Thomas Kuner,Andreas von Deimling,Andreas von Deimling,Wolfgang Wick,Wolfgang Wick,Frank Winkler,Frank Winkler +61 more
TL;DR: It is shown that many tumour cells in astrocytomas extend ultra-long membrane protrusions, and use these distinct tumour microtubes as routes for brain invasion, proliferation, and to interconnect over long distances, which develops functional multicellular network structures.
Journal ArticleDOI
Gadolinium Retention in the Dentate Nucleus and Globus Pallidus Is Dependent on the Class of Contrast Agent
Alexander Radbruch,Lukas D. Weberling,Pascal J. Kieslich,Oliver Eidel,Sina Burth,Philipp Kickingereder,Sabine Heiland,Wolfgang Wick,Heinz Peter Schlemmer,Martin Bendszus +9 more
TL;DR: This study indicates that an SI increase in the DN and GP on T1-weighted images is caused by serial application of the linear GBCA gadopentetate dimeglumine but not by the macrocyclic GBCAs gadoterate meglumines.
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Stroke Magnetic Resonance Imaging Is Accurate in Hyperacute Intracerebral Hemorrhage: A Multicenter Study on the Validity of Stroke Imaging
Jochen B. Fiebach,Peter D. Schellinger,Achim Gass,Thomas Kucinski,Mario Siebler,Arno Villringer,Peter Ölkers,Jochen G. Hirsch,Sabine Heiland,Philipp Wilde,Olav Jansen,Joachim Röther,Werner Hacke,Klaus Sartor +13 more
TL;DR: Hyperacute ICH causes a characteristic imaging pattern on stroke MRI and is detectable with excellent accuracy and can rule out ICH and demonstrate the underlying pathology in hyperacute stroke.
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Hemostatic Therapy in Experimental Intracerebral Hemorrhage Associated With the Direct Thrombin Inhibitor Dabigatran
Wei Zhou,Sönke Schwarting,Sergio Illanes,Arthur Liesz,Moritz Middelhoff,Markus Zorn,Martin Bendszus,Sabine Heiland,Joanne van Ryn,Roland Veltkamp +9 more
TL;DR: There is strong evidence that PCC and, less consistently, fresh-frozen plasma prevent excess intracerebral hematoma expansion in a murine ICH model associated with dabigatran, and the efficacy and safety of this strategy must be further evaluated in clinical studies.
Journal ArticleDOI
IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma.
Philipp Kickingereder,Felix Sahm,Alexander Radbruch,Wolfgang Wick,Sabine Heiland,Andreas von Deimling,Martin Bendszus,Benedikt Wiestler +7 more
TL;DR: It is shown that IDH mutation status is associated with a distinct angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging and the potential future of radiogenomics is highlighted towards a more accurate diagnostic workup of brain tumors.