S
Sabine Schweizer
Researcher at Technische Universität München
Publications - 6
Citations - 404
Sabine Schweizer is an academic researcher from Technische Universität München. The author has contributed to research in topics: Thermogenin & Thermogenesis. The author has an hindex of 5, co-authored 6 publications receiving 278 citations. Previous affiliations of Sabine Schweizer include University Hospital Regensburg.
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Journal ArticleDOI
The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
Alida S.D. Kindt,Gerhard Liebisch,Thomas Clavel,Thomas Clavel,Dirk Haller,Gabriele Hörmannsperger,Hongsup Yoon,Daniela Kolmeder,Alexander Sigruener,Sabrina Krautbauer,Claudine Seeliger,Alexandra Ganzha,Sabine Schweizer,Rosalie Morisset,Till Strowig,Hannelore Daniel,Dominic Helm,Bernhard Kuster,Jan Krumsiek,Josef Ecker +19 more
TL;DR: Mechanistic investigations reveal that acetate originating from gut microbial degradation of dietary fiber serves as precursor for hepatic synthesis of C16 and C18 fatty acids and their related glycerophospholipid species that are also released into the circulation.
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Taking control over intracellular fatty acid levels is essential for the analysis of thermogenic function in cultured primary brown and brite/beige adipocytes
TL;DR: It is demonstrated that U CP1 is functionally thermogenic in intact brite adipocytes and adrenergic UCP1 activation is largely dependent on adipose triglyceride lipase (ATGL) rather than hormone sensitive lipase(HSL) instead of hormone sensitivelipase (HSL).
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Quantification of Fecal Short Chain Fatty Acids by Liquid Chromatography Tandem Mass Spectrometry—Investigation of Pre-Analytic Stability
Gerhard Liebisch,Josef Ecker,Sebastian Roth,Sabine Schweizer,Veronika Öttl,Hans-Frieder Schött,Hongsup Yoon,Dirk Haller,Ernst Holler,Ralph Burkhardt,Silke Matysik +10 more
TL;DR: A fast and reproducible method for the quantification of SCFAs in fecal samples by liquid chromatography tandem mass spectrometry (LC-MS/MS) upon derivatization to 3-nitrophenylhydrazones (3NPH).
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The lipidome of primary murine white, brite, and brown adipocytes—Impact of beta-adrenergic stimulation
Sabine Schweizer,Gerhard Liebisch,Josef Oeckl,Marcus Hoering,Claudine Seeliger,Carolin Schiebel,Martin Klingenspor,Josef Ecker +7 more
TL;DR: Together, the brite and brown lipidome was comparable and indicates differences in membrane lipid packing density compared with white adipocytes, and changes in ceramide species profile could be related to the degree of browning.
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Substrate fluxes in brown adipocytes upon adrenergic stimulation and uncoupling protein 1 ablation.
TL;DR: In this article, the authors determined and inferred the flux of a number of key catabolic metabolites, their changes in response to adrenergic stimulation, and the dependency on the thermogenic uncoupling protein 1 and/or oxidative phosphorylation.