Saer Doumett

TL;DR: GYSMNP@PF127 shows high promise as dual exogenous (AC field)/endogenous (pH) stimuli-responsive actuators for targeted thermo-chemotherapy, combining magnetic hyperthermia and controlled drug release triggered by the abnormal tumour environment.

TL;DR: Generation of oxidative lesions may be a mechanism by which magnetic hyperthermia induces cancer cell death, and dose–response relationships were observed.

TL;DR: These encapsulated iron oxide nanoparticles exhibit strong super-paramagnetic behavior and nuclear relaxivities that make them useful as magnetic resonance imaging (MRI) contrast media as well and could enable the development of a PA probe with magnetic and spectroscopic properties suitable for in vitro and in vivo real-time imaging of relevant biological targets.

TL;DR: In this article, the authors proposed a radiofrequency (RF) radiating system for highly focused hyperthermia with magnetic nanoparticles, where a coil was designed to focus the magnetic field at the frequency that maximizes the heat release from the chosen nanoparticles.

TL;DR: Efficient accumulation, in vivo, of EGF-coated nanoparticles in subcutaneous xenograft tumor tissues in sufficient amounts to be able to mediate visualization by magnetic resonance imaging may warrant novel and very efficient theranostic approaches to HNSCC.