S
Sai Prasad N. Iyer
Researcher at Schering-Plough
Publications - 2
Citations - 1676
Sai Prasad N. Iyer is an academic researcher from Schering-Plough. The author has contributed to research in topics: Intestinal cholesterol absorption & HMG-CoA reductase. The author has an hindex of 2, co-authored 2 publications receiving 1569 citations.
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Journal ArticleDOI
Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.
Scott W. Altmann,Harry R. Davis,Li-ji Zhu,Xiaorui Yao,Lizbeth M. Hoos,Glen Tetzloff,Sai Prasad N. Iyer,Maureen Maguire,Andrei Golovko,Ming Zeng,Luquan Wang,Nicholas J. Murgolo,Michael P. Graziano +12 more
TL;DR: It is shown that Niemann-Pick C1Like 1(NPC1L1) protein plays a critical role in the absorption of intestinal cholesterol, and resides in an ezetimibe-sensitive pathway responsible for intestinal cholesterol absorption.
Journal ArticleDOI
Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein
Sai Prasad N. Iyer,Xiaorui Yao,James H. Crona,Lizbeth M. Hoos,Glen Tetzloff,Harry R. Davis,Michael P. Graziano,Scott W. Altmann +7 more
TL;DR: Biochemical data indicate that NPC1L1 exists as a predominantly cell surface membrane expressed protein, consistent with its proposed role as the putative intestinal sterol transporter.