Saija Koskimies

TL;DR: The tools developed to perform this study, the largest population study of its kind yet performed, can now be used for other population investigations, including that reported in 1945 in the black U.S. population.

TL;DR: The Xbal polymorphism of the glycogen synthase gene identifies a subgroup of patients with NIDDM characterized by a strong family history of NID DM, a high prevalence of hypertension, and marked insulin resistance.

TL;DR: It is shown that healthy reticulin-antibody-positive first-degree relatives of coeliac disease patients, irrespective of the state of the jejunal mucosa, are genetically similar to known coeliasis disease patients.

TL;DR: Impaired beta cell function is a characteristic feature of many, but not all, NIDD patients who fail on treatment with oral antidiabetic drugs, and the presence of islet cell and thyrogastric antibodies can unmask a distinct group of NIDs patients with a high risk of secondary drug failure and subsequent insulin dependency.

TL;DR: In addition to coexisting macroangiopathy, increased albumin excretion rate, poor glycaemic control and neuropathy are risk factors for cardiovascular mortality in patients with Type II diabetes.