S
Saleh Mahmood
Researcher at University at Buffalo
Publications - 16
Citations - 607
Saleh Mahmood is an academic researcher from University at Buffalo. The author has contributed to research in topics: DNA methylation & Pyruvate dehydrogenase complex. The author has an hindex of 11, co-authored 15 publications receiving 548 citations. Previous affiliations of Saleh Mahmood include Roswell Park Cancer Institute & State University of New York System.
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Journal ArticleDOI
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Ping Liang,Fei Song,Srimoyee Ghosh,Srimoyee Ghosh,Evan Morien,Evan Morien,Maochun Qin,Saleh Mahmood,Saleh Mahmood,Kyoko Fujiwara,Kyoko Fujiwara,Jun Igarashi,Hiroki Nagase,Hiroki Nagase,William A. Held +14 more
TL;DR: The data suggests the vast majority of unique sequence DNA methylation has tissue specificity, that demethylation has a prominent role in tissue differentiation, and that DNAmethylation has regulatory roles in alternative promoter selection and in non-promoter regions.
Journal ArticleDOI
Tissue specific differentially methylated regions (TDMR) : Changes in DNA methylation during development
Fei Song,Saleh Mahmood,Srimoyee Ghosh,Ping Liang,Domminic J. Smiraglia,Hiroki Nagase,Hiroki Nagase,William A. Held +7 more
TL;DR: The results suggest that methylation changes during development are dynamic, involve demethylation and methylation, and may occur at late stages of embryonic development or even postnatally.
Journal ArticleDOI
Inactivation of the Murine Pyruvate Dehydrogenase (Pdha1) Gene and Its Effect on Early Embryonic Development
Mark T. Johnson,Saleh Mahmood,Susannah L. Hyatt,Hsin-Sheng Yang,Paul D. Soloway,Richard W. Hanson,Mulchand S. Patel +6 more
TL;DR: An essential role for oxidative metabolism of glucose during the early postimplantation period of prenatal development is demonstrated.
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Intermediary metabolism and energetics during murine early embryogenesis.
TL;DR: Several approaches that have been used to investigate embryonic metabolism will be considered, with a special emphasis being given to recently introduced mutations affecting pathways implicated in energy homeostasis of the early embryo.
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Developmental programming in skeletal muscle in response to overnourishment in the immediate postnatal life in rats.
TL;DR: The results suggest that epigenetic modifications of the key genes involved in the insulin signaling pathway in skeletal muscle could result in the development of insulin resistance in SL female rats.