S
Sally Ross
Researcher at Food and Drug Administration
Publications - 14
Citations - 3368
Sally Ross is an academic researcher from Food and Drug Administration. The author has contributed to research in topics: Biomarker discovery & Pancreatic cancer. The author has an hindex of 12, co-authored 14 publications receiving 3131 citations. Previous affiliations of Sally Ross include Brookhaven National Laboratory & National Institutes of Health.
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Journal ArticleDOI
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
Sunil R. Hingorani,Emanuel F. Petricoin,Anirban Maitra,Vinodh N. Rajapakse,Catrina King,Michael A. Jacobetz,Sally Ross,Thomas P. Conrads,Timothy D. Veenstra,Ben A. Hitt,Yoshiya Kawaguchi,Donald J. Johann,Lance A. Liotta,Howard C. Crawford,Mary E. Putt,Tyler Jacks,Christopher V.E. Wright,Ralph H. Hruban,Andrew M. Lowy,David A. Tuveson +19 more
TL;DR: It is found that physiological levels of Kras(G12D) induce ductal lesions that recapitulate the full spectrum of human pancreatic intraepithelial neoplasias (PanINs), putative precursors to invasive pancreatic cancer.
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High-resolution serum proteomic features for ovarian cancer detection.
Thomas P. Conrads,Vincent A. Fusaro,Sally Ross,Donald J. Johann,Vinodh N. Rajapakse,Ben A. Hitt,Seth M. Steinberg,Elise C. Kohn,David A. Fishman,Gordon Whitely,J C Barrett,Lance A. Liotta,Emanuel F. Petricoin,Timothy D. Veenstra +13 more
TL;DR: It is concluded that the use of high-resolution MS yields superior classification patterns as compared with those obtained with lower resolution instrumentation, and multiple and distinct proteomic patterns, comprising low molecular weight biomarkers, detected by high- resolution MS achieve accuracies surpassing individual biomarker classifiers, warranting validation in a large clinical study.
Journal ArticleDOI
Biomarker amplification by serum carrier protein binding
Arpita I. Mehta,Sally Ross,Mark S. Lowenthal,Vincent A. Fusaro,David A. Fishman,Emanuel F. Petricoin,Lance A. Liotta +6 more
TL;DR: The majority of low molecular mass biomarkers exist bound to carrier proteins, and the pattern of LMM biomarkers bound specifically to albumin is distinct from those bound to non-albumin carriers.
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Serum proteomic profiling can discriminate prostate cancer from benign prostates in men with total prostate specific antigen levels between 2.5 and 15.0 ng/ml
David K. Ornstein,Walter Rayford,Vincent A. Fusaro,Thomas P. Conrads,Sally Ross,Ben A. Hitt,Wesley W. Wiggins,Timothy D. Veenstra,Lance A. Liotta,Emanuel F. Petricoin +9 more
TL;DR: It is demonstrated that high resolution mass spectroscopy can generate serum proteomic patterns that discriminate men with elevated PSA due to benign processes from men with CaP even when PSA is within the diagnostic gray zone.
Journal ArticleDOI
Discovering clinical biomarkers of ionizing radiation exposure with serum proteomic analysis.
Cynthia Ménard,Donald J. Johann,Mark Lowenthal,Thierry Muanza,Thierry Muanza,Mary Sproull,Sally Ross,James L. Gulley,Emanuel F. Petricoin,C. Norman Coleman,Gordon Whiteley,Lance A. Liotta,Kevin Camphausen +12 more
TL;DR: The composition of proteins in serum seems to change with ionizing radiation exposure, and proteomic analysis for the discovery of clinical biomarkers of radiation exposure warrants further study.