scispace - formally typeset
S

Salvatore Curello

Researcher at University of Brescia

Publications -  159
Citations -  7039

Salvatore Curello is an academic researcher from University of Brescia. The author has contributed to research in topics: Ischemia & Oxidative stress. The author has an hindex of 41, co-authored 151 publications receiving 6334 citations. Previous affiliations of Salvatore Curello include University of Ferrara.

Papers
More filters
Journal Article

Oxidative stress during myocardial ischaemia and heart failure

TL;DR: In this paper, the authors showed that the immunological response to heart failure may result in endothelial and myocyte dysfunction through oxidative stress-mediated apoptosis, where tumour necrosis factor causes a rapid rise in intracellular reactive oxygen intermediates and apoptosis.
Journal ArticleDOI

Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial

Pascal Vranckx, +188 more
- 15 Sep 2018 - 
TL;DR: The GLOBAL LEADERS trial as discussed by the authors showed that ticagrelor, in combination with aspirin for 1 month, followed by ticaragrelor alone, improves outcomes after percutaneous coronary intervention compared with standard antiplatelet regimens.
Journal ArticleDOI

Occurrence of oxidative stress during reperfusion of the human heart.

TL;DR: Data suggest for the first time that, depending on the severity of the ischemic period, oxidative stress occurs during reperfusion of patients with coronary artery disease who are subjected to heart surgery and that it may be linked with a delay in postoperative recovery of cardiac function.
Journal ArticleDOI

Apoptosis of Endothelial Cells Precedes Myocyte Cell Apoptosis in Ischemia/Reperfusion Injury

TL;DR: The radial spread of apoptosis to surrounding cardiac myocytes suggests that reperfusion induces the release of soluble pro-apoptotic mediators from endothelial cells that promote myocyte apoptosis.