D
Dik Heg
Researcher at University of Bern
Publications - 293
Citations - 12961
Dik Heg is an academic researcher from University of Bern. The author has contributed to research in topics: Percutaneous coronary intervention & Myocardial infarction. The author has an hindex of 52, co-authored 249 publications receiving 10251 citations. Previous affiliations of Dik Heg include University of Basel & University of Groningen.
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Journal ArticleDOI
Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial
Marco Valgimigli,Andrea Gagnor,Paolo Calabrò,Enrico Frigoli,Sergio Leonardi,Tiziana Zaro,Paolo Rubartelli,Carlo Briguori,Giuseppe Andò,Alessandra Repetto,Ugo Limbruno,Bernardo Cortese,Paolo Sganzerla,Alessandro Lupi,Mario Galli,Salvatore Colangelo,Salvatore Ierna,Arturo Ausiello,Patrizia Presbitero,Gennaro Sardella,Ferdinando Varbella,Giovanni Esposito,Andrea Santarelli,Simone Tresoldi,Marco Stefano Nazzaro,Antonio Zingarelli,Nicoletta De Cesare,Stefano Rigattieri,Paolo Tosi,Cataldo Palmieri,Salvatore Brugaletta,Sunil V. Rao,Dik Heg,Martina Rothenbühler,Pascal Vranckx,Peter Jüni +35 more
TL;DR: In patients with acute coronary syndrome undergoing invasive management, radial as compared with femoral access reduces net adverse clinical events, through a reduction in major bleeding and all-cause mortality.
Journal ArticleDOI
Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials
Francesco Costa,Francesco Costa,Francesco Costa,David van Klaveren,David van Klaveren,Stefan James,Dik Heg,Lorenz Räber,Fausto Feres,Thomas Pilgrim,Myeong Ki Hong,Hyo-Soo Kim,Antonio Colombo,Philippe Gabriel Steg,Thomas Zanchin,Tullio Palmerini,Lars Wallentin,Deepak L. Bhatt,Gregg W. Stone,Stephan Windecker,Ewout W. Steyerberg,Marco Valgimigli,Marco Valgimigli +22 more
TL;DR: The PRECISE-DAPT score is a simple five-item risk score, which provides a standardised tool for the prediction of out-of-hospital bleeding during DAPT and can support clinical decision making for treatment duration.
Journal ArticleDOI
Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial
Giulio G. Stefanini,Bindu Kalesan,Patrick W. Serruys,Dik Heg,Paweł Buszman,Axel Linke,Thomas Ischinger,Volker Klauss,Franz R. Eberli,William Wijns,Marie-Claude Morice,Carlo Di Mario,Roberto Corti,Diethmar Antoni,Hae Y. Sohn,Pedro Eerdmans,Gerrit-Anne van Es,Bernhard Meier,Stephan Windecker,Peter Jüni +19 more
TL;DR: Biodegradable polymer BES are non-inferior to durable polymer SES and, by reducing the risk of cardiac events associated with very late ST, might improve long-term clinical outcomes for up to 4 years compared with durable polymerSES.
Journal ArticleDOI
Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes
Marco Valgimigli,Enrico Frigoli,Sergio Leonardi,Martina Rothenbühler,Andrea Gagnor,Paolo Calabrò,Stefano Garducci,Paolo Rubartelli,Carlo Briguori,Giuseppe Andò,Alessandra Repetto,Ugo Limbruno,Roberto Garbo,Paolo Sganzerla,Filippo Russo,Alessandro Lupi,Bernardo Cortese,Arturo Ausiello,Salvatore Ierna,Giovanni Esposito,Patrizia Presbitero,Andrea Santarelli,Gennaro Sardella,Ferdinando Varbella,Simone Tresoldi,Nicoletta De Cesare,Stefano Rigattieri,Antonio Zingarelli,Paolo Tosi,Arnoud W J van 't Hof,Giacomo Boccuzzi,Elmir Omerovic,Manel Sabaté,Dik Heg,Peter Jüni,Pascal Vranckx +35 more
TL;DR: In patients with an acute coronary syndrome, the rates of major adverse cardiovascular events and net adverse clinical events were not significantly lower with bivalirudin than with unfractionated heparin.
Journal ArticleDOI
Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial
Pascal Vranckx,Marco Valgimigli,Peter Jüni,Christian W. Hamm,Philippe Gabriel Steg,Philippe Gabriel Steg,Dik Heg,Gerrit Anne van Es,Eùgene P. McFadden,Yoshinobu Onuma,Cokky van Meijeren,Ply Chichareon,Edouard Benit,Helge Möllmann,Luc Janssens,Maurizio Ferrario,Aris Moschovitis,Aleksander Zurakowski,Marcello Dominici,Robert-Jan van Geuns,Kurt Huber,Ton Slagboom,Patrick W. Serruys,Patrick W. Serruys,Stephan Windecker,Mohamed Abdellaoui,David Adlam,Ibrahim Akin,Agustin Albarran Gonzalez-Trevilla,Manuel de Sousa Almeida,Pedro Alves Lemos Neto,Adel Aminian,Richard A. Anderson,Rick Andreae,Michael Angioi,Taku Asano,Emanuele Barbato,Peter Barlis,Pascal Barraud,Olivier F. Bertrand,Farzin Beygui,Leonardo Bolognese,Roberto Botelho,Coby Bouwman,Marco Bressers,Philippe Brunel,Paweł Buszman,Ian Buysschaert,Pedro Canas da Silva,Didier Carrié,Angel Cequier,Chun Chin Chang,Saqib Chowdhary,Carlos Collet,Antonio Colombo,James Cotton,Rui Cruz Ferreira,Salvatore Curello,Nick Curzen,Judith de Bot,Tone de Vreede,Georg Delle Karth,Lynn Dijksma,István Édes,Eric Eeckhout,Ingo Eitel,József Faluközy,Farzin Fath-Ordoubadi,Géza Fontos,Jose Francisco Diaz,Edgard Freitas Quintella,Bernhard Frey,Guy Friedrich,Gavin Galasko,Grzegorz Galuszka,Vasco Gama Ribeiro,Scot Garg,Giuseppe Gargiulo,Tobias Geisler,Valeri Gelev,Art Ghandilyan,Javier Goicolea,Tommaso Gori,Felice Gragnano,Ana H.C. Guimarães,Michael Haude,Pieter Heijke,Rosa Ana Hernández Antolin,David Hildick-Smith,Dorien Hillen,Ina Hoekman,Sjoerd H. Hofma,Lene Holmvang,Stephen P. Hoole,Iván Horváth,Annemarie Hugense,Karim Ibrahim,Andrés Iñiguez,Karl Isaaz,Zoltan Jambrik,Pawel Jasionowicz,Judith Jonk,Werner Jung,Yuki Katagiri,Norihiro Kogame,Tian Hai Koh,René Koning,Mariana Konteva,Zsolt Kőszegi,Florian Krackhardt,Yvonne Kreuger,Neville Kukreja,Boudijn Ladan,Pierre Lantelme,Sergio Leandro,Gregor Leibundgut,Christoph Liebetrau,Wietze Lindeboom,Carlos Macaya Miguel,François Mach,Michael Magro,Luc Maillard,Negar Manavifar,Laura Mauri,Eugene P. McFadden,Béla Merkely,Yosuke Miyazaki,Adam Młodziankowski,Tiziano Moccetti,Rodrigo Modolo,Helge Möllman,Jean-François Morelle,Michael Munndt Ottesen,Martin Muurling,Christoph Naber,Franz-Josef Neumann,Keith G. Oldroyd,Paul J.L. Ong,Sanne Palsrok,Ivo Petrov,Sylvain Plante,Janusz Prokopczuk,Tessa Rademaker-Havinga,Christopher Raffel,Benno J. Rensing,Marco Roffi,Kees-Jan Royaards,Manel Sabaté,Volker Schächinger,Tim Seidler,Antonio Serra Peñaranda,Patrick W. Serruys,Lali Sikarulidze,Osama Ibrahim Ibrahim Soliman,Amanda Sousa,Ernest Spitzer,Rod Stables,Gabriel Steg,Clemens Steinwender,Eduardas Subkovas,Harry Suryapranata,Kuniaki Takahashi,Suneel Talwar,Emmanuel Teiger,Addy ter Weele,Eva Teurlings,Attila Thury,Jan Tijssen,Gincho Tonev,Diana Trendafilova-Lazarova,Carlo Tumscitz,Victor A. Umans,Imre Ungi,Veselin Valkov,Pim van der Harst,Dobrin Vassilev,Vasil Velchev,Esther Velthuizen,Freek W.A. Verheugt,Natalia Vlcek,Jürgen vom Dahl,Mathias Vrolix,Simon J Walsh,Nikos Werner,Maarten Witsenburg,Azfar Zaman,Krzysztof Żmudka,Bernhard Zrenner,Robert Zweiker +188 more
TL;DR: The GLOBAL LEADERS trial as discussed by the authors showed that ticagrelor, in combination with aspirin for 1 month, followed by ticaragrelor alone, improves outcomes after percutaneous coronary intervention compared with standard antiplatelet regimens.