Samuel M.S. Cheng

TL;DR: Two 1-step quantitative real-time reverse-transcription PCR assays can achieve a rapid detection of 2019n-CoV in human samples, thereby allowing early identification of patients.

TL;DR: In this paper , the authors showed that a 50% plaque reduction neutralization antibody titer (PRNT50) ≥ 25.6 in their live virus assay corresponded to the threshold for 50% protection from infection against wild-type (WT) SARS-CoV-2 Omicron variant.

TL;DR: In this article, Wu et al. showed that SARS-CoV-2 infection elicits robust neutralizing antibody titres in most individuals, even after accounting for severity.

TL;DR: It was found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness, however, virus RNA was detectable for many weeks by reverse transcription PCR.

TL;DR: A recently developed surrogate virus neutralization test (sVNT) in comparison to 90% plaque reduction neutralization tests (PRNT90) in human, canine, cat, and hamster sera is evaluated and the lack of cross-reactivity to other coronaviruses in SARS-CoV-2 sVNT and PRNT90 is confirmed.