S
Sankar Ghosh
Researcher at Columbia University
Publications - 211
Citations - 62247
Sankar Ghosh is an academic researcher from Columbia University. The author has contributed to research in topics: Signal transduction & Transcription factor. The author has an hindex of 89, co-authored 203 publications receiving 57399 citations. Previous affiliations of Sankar Ghosh include Howard Hughes Medical Institute & Yale University.
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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
TL;DR: Recently, significant advances have been made in elucidating the details of the pathways through which signals are transmitted to the NF-kappa B:I kappa B complex in the cytosol and their implications for the study of NF-Kappa B.
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Shared principles in NF-kappaB signaling
Matthew S. Hayden,Sankar Ghosh +1 more
TL;DR: The authors synthesize some of the basic principles that have emerged from studies of NF-kappaB, and aim to generate a more unified view of the regulation of the transcription factor.
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Signaling to NF-kappaB.
Matthew S. Hayden,Sankar Ghosh +1 more
TL;DR: An overview of established NF-kappaB signaling pathways is provided with focus on the current state of research into the mechanisms that regulate IKK activation and NF- kappaB transcriptional activity.
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Missing Pieces in the NF-κB Puzzle
Sankar Ghosh,Michael Karin +1 more
TL;DR: In this paper, a review of recent progress as well as unanswered questions regarding the regulation and function of NF-kappaB and IKK is presented, focusing on recent progress and unanswered questions.
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The NF-κB Family of Transcription Factors and Its Regulation
Andrea Oeckinghaus,Sankar Ghosh +1 more
TL;DR: The NF-kappaB pathway is a paradigm for understanding general principles of signal transduction and gene regulation as well as other pathway-specific mediators, and the transcription factors are themselves extensively modified.