S
Sara Perteghella
Researcher at University of Pavia
Publications - 70
Citations - 1745
Sara Perteghella is an academic researcher from University of Pavia. The author has contributed to research in topics: Mesenchymal stem cell & Drug delivery. The author has an hindex of 20, co-authored 62 publications receiving 1147 citations. Previous affiliations of Sara Perteghella include San Antonio River Authority.
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Journal ArticleDOI
Mesenchymal stem/stromal cell extracellular vesicles: From active principle to next generation drug delivery system
Barbara Crivelli,Theodora Chlapanidas,Sara Perteghella,Enrico Lucarelli,Luisa Pascucci,Anna T. Brini,Ivana Ferrero,Mario Marazzi,Augusto Pessina,Maria Luisa Torre +9 more
TL;DR: This review focuses on MSCs and their EVs as APIs, as well as DDS, considering their ability to reach inflamed and damaged tissues and to prolong the release of encapsulated drugs.
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Sericins exhibit ROS-scavenging, anti-tyrosinase, anti-elastase, and in vitro immunomodulatory activities.
Theodora Chlapanidas,Silvio Faragò,Giulia Lucconi,Sara Perteghella,Marta Galuzzi,Melissa Mantelli,Maria Antonietta Avanzini,Marta Cecilia Tosca,Mario Marazzi,Daniele Vigo,Maria Luisa Torre,Massimo Faustini +11 more
TL;DR: A mixture of sericins extracted from the most promising strains may be useful for dermatological and cosmetic use.
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Mesenchymal Stromal Cell Secretome for Severe COVID-19 Infections: Premises for the Therapeutic Use.
Elia Bari,Ilaria Ferrarotti,Laura Saracino,Sara Perteghella,Maria Luisa Torre,Angelo Corsico +5 more
TL;DR: In the authors' opinion, mesenchymal stem cell secretome could offer a new therapeutic approach in treating COVID-19 pneumonia, due to the broad pharmacological effects it shows, including anti-inflammatory, immunomodulatory, regenerative, pro-angiogenic and anti-fibrotic properties.
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Pilot Production of Mesenchymal Stem/Stromal Freeze-Dried Secretome for Cell-Free Regenerative Nanomedicine: A Validated GMP-Compliant Process
Elia Bari,Sara Perteghella,Dario Di Silvestre,Marzio Sorlini,Laura Catenacci,Milena Sorrenti,Giorgio Marrubini,Rossana Rossi,Giuseppe Tripodo,Pierluigi Mauri,Mario Marazzi,Maria Luisa Torre +11 more
TL;DR: A pilot production process for mesenchymal stem/stromal freeze-dried secretome was performed in a validated good manufacturing practice (GMP)-compliant cell factory and showed to in vitro counteract the oxidative stress damage induced by H2O2 on nucleus pulposus cells by MTT assay.
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Silk fibroin nanoparticles for celecoxib and curcumin delivery: ROS-scavenging and anti-inflammatory activities in an in vitro model of osteoarthritis
Barbara Crivelli,Elia Bari,Sara Perteghella,Laura Catenacci,Milena Sorrenti,Michela Mocchi,Silvio Faragò,Giuseppe Tripodo,Adriele Prina-Mello,Maria Luisa Torre +9 more
TL;DR: In this article, Silk fibroin nanoparticles (SFNs) promote anti-inflammatory properties of celecoxib (CXB) or curcumin (CUR), and could be exploited for osteoarthritis (OA) treatment.