Sara T. Al-Rashood

TL;DR: A machine learning based approach for energy management in renewable microgrids considering a reconfigurable structure based on remote switching of tie and sectionalizing and a self-adaptive modification is suggested, which helps the solutions pick the modification method that best fits their situation.

TL;DR: In this paper, a structural extension approach was adopted via N-alkylation and N-benzylation of isatin moiety to enhance the tail hydrophobic interactions within the carbonic anhydrase (CA) IX active site.

TL;DR: Compound 5l stood out as the most potent pyridine derivative, at US-NCI Developmental Therapeutic Program anticancer assay, with broad-spectrum antitumor activity against the most tested cancer cell lines from all subpanels.

TL;DR: Spirooxindole 6a was found to be an efficient anti-proliferative agent towards both HepG2 and PC-3 cells and assessed for its apoptosis induction potential in HepG1 cells, where its pro-apoptotic impact was approved via the significant elevation in the Bax/Bcl-2 ratio and the expression levels of caspase-3.

TL;DR: Sulfonamide 9e displayed good selectivity profile for inhibition of the tumor-associated isoforms (CAs IX & XII) over the off-target cytosolic CAs I and II, and was found to be the most potent counterpart against HCT-116.