Sarah Holden

TL;DR: It is shown that intravenously injected radioiodinated S1 readily crossed the blood-brain barrier (BBB) in male mice, was taken up by brain regions and entered the parenchymal brain space, and I-S1 uptake in the hippocampus and olfactory bulb was reduced by lipopolysaccharide-induced inflammation.

TL;DR: In this article, the genotype-dependent associations include members of the Lachnospiraceae and Ruminococcaceae families and the Apoe gene were found to be significantly more methylated in AppNL-G-F than WT mice.

TL;DR: In this paper, the authors characterized behavioral and cognitive performance of male WAG/Rij rats 3 months after sham-irradiation or total body irradiation with a simplified 5-ion mixed beam exposure in the absence or presence of simulated weightlessness using hindlimb unloading (HU) alone.

TL;DR: The results show that it is feasible to behaviorally test germ-free mice inside a biosafety cabinet, however, the host genotype was critical in modulating the pattern of induced behavioral phenotypes as compared to those seen in the genotype- and sex-match donor mice.

TL;DR: In this paper, the effects of acute and chronic exposure to a mixed field of neutrons and photons and single or fractionated simulated galactic cosmic ray exposure (GCRsim) on behavioral and cognitive performance in mice were assessed.