Kimberly A. Nevonen

TL;DR: The assembly and analysis of a northern white-cheeked gibbon genome is presented and the propensity for a gibbon-specific retrotransposon (LAVA) to insert into chromosome segregation genes and alter transcription by providing a premature termination site is described, suggesting a possible molecular mechanism for the genome plasticity of the gibbon lineage.

TL;DR: It is found that gibbon rearrangements occur at TAD boundaries, independent of the parameters used to identify TADs, and it is shown that limited epigenetic homogenization occurs across breakpoints, irrespective of their time of occurrence in the gibbon lineage.

TL;DR: The results provide valuable context for understanding the history of admixture in primates, including in the authors' own lineage, and suggest a complex process of intermittent contact that has occurred multiple times in baboon evolutionary history, despite no obvious fitness costs to hybrids or major geographic or behavioural barriers.

TL;DR: It is suggested that embryos respond to chromosomal errors by encapsulation into micronuclei, elimination via cellular fragmentation, and selection against highly aneuploid blastomeres to overcome chromosome instability during preimplantation development.

TL;DR: It is suggested that embryos respond to chromosomal errors by encapsulation into micronuclei, elimination by cellular fragmentation, and selection against highly aneuploid blastomeres to overcome chromosome instability during preimplantation development.