S
Sarah J. Nelson
Researcher at University of California, San Francisco
Publications - 292
Citations - 24417
Sarah J. Nelson is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Magnetic resonance spectroscopic imaging & Magnetic resonance imaging. The author has an hindex of 86, co-authored 291 publications receiving 22507 citations. Previous affiliations of Sarah J. Nelson include University of California & University of California, Berkeley.
Papers
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Journal ArticleDOI
Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma
Brett E. Johnson,Tali Mazor,Chibo Hong,Michael R. Barnes,Koki Aihara,Cory Y. McLean,Shaun D. Fouse,Shogo Yamamoto,Hiroki R. Ueda,Kenji Tatsuno,Saurabh Asthana,Llewellyn E. Jalbert,Sarah J. Nelson,Andrew W. Bollen,W. Clay Gustafson,Elise Charron,William A. Weiss,Ivan Smirnov,Jun S. Song,Adam B. Olshen,Soonmee Cha,Yongjun Zhao,Richard A. Moore,Andrew J. Mungall,Steven J.M. Jones,Martin Hirst,Marco A. Marra,Nobuhito Saito,Hiroyuki Aburatani,Akitake Mukasa,Mitchel S. Berger,Susan M. Chang,Barry S. Taylor,Joseph F. Costello +33 more
TL;DR: Exome sequencing of exomes of 23 initial low-grade gliomas and recurrent tumors resected from the same patients suggests that recurrent tumors are often seeded by cells derived from the initial tumor at a very early stage of their evolution.
Journal ArticleDOI
Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate
Sarah J. Nelson,John Kurhanewicz,Daniel B. Vigneron,Peder E. Z. Larson,Andrea L. Harzstark,Marcus Ferrone,Mark Van Criekinge,Jose W. Chang,Robert Bok,Ilwoo Park,Galen D. Reed,Lucas Carvajal,Eric J. Small,Pamela N. Munster,Vivian Weinberg,Jan Henrik Ardenkjær-Larsen,Albert P. Chen,Ralph E. Hurd,Liv-Ingrid Odegardstuen,Fraser Robb,James Tropp,Jonathan Alan Murray +21 more
TL;DR: This first-in-man imaging study evaluated the safety and feasibility of hyperpolarized [1-13C]pyruvate as an agent for noninvasively characterizing alterations in tumor metabolism for patients with prostate cancer and showed elevated levels of lactate, alanine, and bicarbonate in regions of biopsy-proven cancer.
Journal ArticleDOI
Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.7-cm3) spatial resolution.
John Kurhanewicz,Daniel B. Vigneron,Hedvig Hricak,Perinchery Narayan,Peter R. Carroll,Sarah J. Nelson +5 more
TL;DR: The results suggest that a 3D MRSI examination added to a clinical MR imaging examination may help define the presence and spatial extent of prostate cancer.
Journal ArticleDOI
Prostate cancer: localization with three-dimensional proton MR spectroscopic imaging--clinicopathologic study.
Juergen Scheidler,Hedvig Hricak,Daniel B. Vigneron,Kyle K. Yu,D L Sokolov,L R Huang,Charles Zaloudek,Sarah J. Nelson,Peter R. Carroll,John Kurhanewicz +9 more
TL;DR: The addition of 3D MR spectroscopic imaging to MR imaging provides better detection and localization of prostate cancer in a sextant of the prostate than does use of MR imaging alone.
Journal ArticleDOI
Hyperpolarized 13C Lactate, Pyruvate, and Alanine: Noninvasive Biomarkers for Prostate Cancer Detection and Grading
Mark J. Albers,Robert Bok,Albert P. Chen,Charles H. Cunningham,Matt L. Zierhut,Vickie Zhang,Susan J. Kohler,James Tropp,Ralph E. Hurd,Yi-Fen Yen,Sarah J. Nelson,Daniel B. Vigneron,John Kurhanewicz +12 more
TL;DR: Elevated hyperpolarized lactate and potentially THC and alanine are noninvasive biomarkers of prostate cancer presence and histologic grade that could be used in future three-dimensional (13)C spectroscopic imaging studies of prostatecancer patients.