S
Sarah J. Vermont
Researcher at University of Liverpool
Publications - 5
Citations - 336
Sarah J. Vermont is an academic researcher from University of Liverpool. The author has contributed to research in topics: Neospora caninum & Neospora. The author has an hindex of 5, co-authored 5 publications receiving 292 citations.
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Journal ArticleDOI
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy
Adam J. Reid,Sarah J. Vermont,James Cotton,David Harris,Grant A. Hill-Cawthorne,Stephanie Könen-Waisman,Sophia M. Latham,Tobias Mourier,Rebecca Norton,Michael A. Quail,Mandy Sanders,Dhanasekaran Shanmugam,Amandeep Sohal,James D. Wasmuth,James D. Wasmuth,Brian P. Brunk,Michael E. Grigg,Jonathan C. Howard,John Parkinson,David S. Roos,Alexander J. Trees,Matthew Berriman,Arnab Pain,Arnab Pain,Jonathan M. Wastling +24 more
TL;DR: The ecological niches occupied by these species are influenced by a relatively small number of gene products which operate at the host-parasite interface and that the dominance of vertical transmission in N. caninum may be associated with the evolution of reduced virulence in this species.
Journal ArticleDOI
Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features.
Abhinay Ramaprasad,Tobias Mourier,Raeece Naeem,Tareq B. Malas,Ehab M. Moussa,Aswini K. Panigrahi,Sarah J. Vermont,Thomas D. Otto,Jonathan M. Wastling,Arnab Pain +9 more
TL;DR: A manual evaluation of these genomes based on strand-specific RNA sequencing and shotgun proteomics from the invasive tachyzoite stages of these two parasites is described and significantly improved the annotation quality in these genomes that would serve as a manually curated dataset for Toxoplasma and Neospora research communities.
Journal ArticleDOI
Identification of Novel Proteins in Neospora caninum Using an Organelle Purification and Monoclonal Antibody Approach
Catherine S. Sohn,Tim T. Cheng,Michael L. Drummond,Eric D. Peng,Sarah J. Vermont,Dong Xia,Stephen J. Cheng,Jonathan M. Wastling,Peter J. Bradley +8 more
TL;DR: This organellar monoclonal antibody approach not only greatly enhances the tools available for Neospora cell biology, but also identifies novel components of the unique biological characteristics of this important veterinary pathogen.
Journal ArticleDOI
Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography.
Kevin Wang,Eric D. Peng,Amy S. Huang,Dong Xia,Sarah J. Vermont,Gaelle Lentini,Maryse Lebrun,Jonathan M. Wastling,Peter J. Bradley +8 more
TL;DR: It is demonstrated that lectin affinity chromatography is an efficient method of identifying new glycosylated parasite-specific proteins that are present in these organelles.
Journal ArticleDOI
A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum.
Ritesh Krishna,Dong Xia,Sanya J. Sanderson,Achchuthan Shanmugasundram,Sarah J. Vermont,Axel Bernal,Gianluca Daniel-Naguib,Fawaz Ghali,Brian P. Brunk,David S. Roos,Jonathan M. Wastling,Andrew R. Jones +11 more
TL;DR: A large‐scale proteogenomics study of two important apicomplexan pathogens: Toxoplasma gondii and Neospora caninum is presented and several examples where the RNA‐Seq evidence can help in correction of the current gene model and in discovery of potential new genes are presented.