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Aswini K. Panigrahi
Researcher at Seattle Biomed
Publications - 43
Citations - 3207
Aswini K. Panigrahi is an academic researcher from Seattle Biomed. The author has contributed to research in topics: RNA editing & Trypanosoma brucei. The author has an hindex of 30, co-authored 39 publications receiving 3039 citations. Previous affiliations of Aswini K. Panigrahi include King Abdullah University of Science and Technology & University of Washington.
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Journal ArticleDOI
Complex management: RNA editing in trypanosomes
TL;DR: A picture of highly organized complexes is emerging that shows that the complex that catalyzes the central steps of editing is partitioned into distinct insertion and deletion editing subcomplexes.
Journal ArticleDOI
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites
Yong H. Woo,Hifzur Rahman Ansari,Thomas D. Otto,Christen M. Klinger,Martin Kolisko,Jan Michálek,Jan Michálek,Alka Saxena,Dhanasekaran Shanmugam,Annageldi Tayyrov,Alaguraj Veluchamy,Shahjahan Ali,Axel Bernal,Javier del Campo,Jaromír Cihlář,Jaromír Cihlář,Pavel Flegontov,Pavel Flegontov,Sebastian G. Gornik,Eva Hajdušková,Aleš Horák,Aleš Horák,Jan Janouškovec,Nicholas J. Katris,Fred D. Mast,Diego Miranda-Saavedra,Diego Miranda-Saavedra,Tobias Mourier,Raeece Naeem,Mridul Nair,Aswini K. Panigrahi,Neil D. Rawlings,Eriko Padron-Regalado,Abhinay Ramaprasad,Nadira Binte Samad,Aleš Tomčala,Aleš Tomčala,Jon Wilkes,Daniel E. Neafsey,Christian Doerig,Chris Bowler,Patrick J. Keeling,David S. Roos,Joel B. Dacks,Thomas J. Templeton,Thomas J. Templeton,Ross F. Waller,Ross F. Waller,Julius Lukeš,Julius Lukeš,Julius Lukeš,Miroslav Oborník,Miroslav Oborník,Arnab Pain +53 more
TL;DR: Insight is provided into how obligate parasites with diverse life strategies arose from a once free-living phototrophic marine alga, and co-regulated with genes encoding the flagellar apparatus supporting the functional contribution of flagella to the evolution of invasion machinery.
Journal ArticleDOI
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei.
Achim Schnaufer,Achim Schnaufer,Aswini K. Panigrahi,Aswini K. Panigrahi,Brian Panicucci,Robert P. Igo,Robert P. Igo,Reza Salavati,Reza Salavati,Kenneth Stuart,Kenneth Stuart +10 more
TL;DR: Regulated repression of TbMP52 blocks editing, which shows that it is a functional component of the editing complex, indicating that editing is essential in the mammalian stage of the life cycle.
Journal ArticleDOI
A comprehensive analysis of Trypanosoma brucei mitochondrial proteome.
Aswini K. Panigrahi,Yuko Ogata,Alena Zíková,Atashi Anupama,Rachel A. Dalley,Nathalie Acestor,Peter J. Myler,Kenneth Stuart +7 more
TL;DR: A total of 2897 proteins representing a substantial proportion of procyclic form cellular proteome were identified, which confirmed the validity of the vast majority of gene predictions and showed that the genes annotated as hypothetical (species specific) were overpredicted.
Journal ArticleDOI
Identification of novel components of Trypanosoma brucei editosomes.
Aswini K. Panigrahi,Achim Schnaufer,Nancy Lewis Ernst,Bingbing Wang,Nicole Carmean,Reza Salavati,Kenneth Stuart +6 more
TL;DR: Nine novel editosome proteins in Trypanosoma brucei are identified by mass spectrometric analysis of functional editosomes that were purified by serial ion exchange/gel permeation chromatography, immunoaffinity chromatography specific to the TbMP63 editosomal protein, or tandem affinity purification based on a tagged RNA editing ligase.