D
David S. Roos
Researcher at University of Pennsylvania
Publications - 215
Citations - 36462
David S. Roos is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Toxoplasma gondii & Gene. The author has an hindex of 88, co-authored 213 publications receiving 33517 citations. Previous affiliations of David S. Roos include Wellcome Trust Sanger Institute & University of Washington.
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Journal ArticleDOI
OrthoMCL: identification of ortholog groups for eukaryotic genomes.
TL;DR: OrthoMCL provides a scalable method for constructing orthologous groups across multiple eukaryotic taxa, using a Markov Cluster algorithm to group (putative) orthologs and paralogs.
Journal ArticleDOI
Genome sequence of the human malaria parasite Plasmodium falciparum
Malcolm J. Gardner,Neil Hall,Eula Fung,Owen White,Matthew Berriman,Richard W. Hyman,Jane M. Carlton,Arnab Pain,Karen E. Nelson,Sharen Bowman,Ian T. Paulsen,Keith D. James,Jonathan A. Eisen,Kim Rutherford,Steven L. Salzberg,Alister Craig,Sue Kyes,Man Suen Chan,Vishvanath Nene,Shamira J. Shallom,Bernard B. Suh,Jeremy Peterson,Samuel V. Angiuoli,Mihaela Pertea,Jonathan E. Allen,Jeremy D. Selengut,Daniel H. Haft,Michael W. Mather,Akhil B. Vaidya,David M. A. Martin,Alan H. Fairlamb,Martin Fraunholz,David S. Roos,Stuart A. Ralph,Geoffrey I. McFadden,Leda M. Cummings,G. Mani Subramanian,Christopher J. Mungall,J. Craig Venter,Daniel J. Carucci,Stephen L. Hoffman,Chris I. Newbold,Ronald W. Davis,Claire M. Fraser,Bart Barrell +44 more
TL;DR: The genome sequence of P. falciparum clone 3D7 is reported, which is the most (A + T)-rich genome sequenced to date and is being exploited in the search for new drugs and vaccines to fight malaria.
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PlasmoDB: a functional genomic database for malaria parasites
Cristina Aurrecoechea,John Brestelli,Brian P. Brunk,Jennifer Dommer,Steve Fischer,Bindu Gajria,Xin Gao,Alan R. Gingle,Gregory R. Grant,Omar S. Harb,Mark Heiges,Frank Innamorato,John Iodice,Jessica C. Kissinger,Eileen Kraemer,Wei Li,John A. Miller,Vishal Nayak,Cary Pennington,Deborah F. Pinney,David S. Roos,Chris Ross,Christian J. Stoeckert,Charles Treatman,Haiming Wang +24 more
TL;DR: PlasmoDB as mentioned in this paper is a functional genomic database for Plasmodium spp. that provides a resource for data analysis and visualization in a gene-by-gene or genome-wide scale.
Journal ArticleDOI
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups
TL;DR: The OrthoMCL-DB provides a centralized warehouse for orthology prediction among multiple species, and will be updated and expanded as additional genome sequence data become available.
Journal ArticleDOI
TriTrypDB: a functional genomic resource for the Trypanosomatidae
Martin Aslett,Cristina Aurrecoechea,Matthew Berriman,John Brestelli,Brian P. Brunk,Mark Carrington,Daniel P. Depledge,Steve Fischer,Bindu Gajria,Xin Gao,Malcolm J. Gardner,Alan R. Gingle,Gregory R. Grant,Omar S. Harb,Mark Heiges,Christiane Hertz-Fowler,Robin Houston,Frank Innamorato,John Iodice,Jessica C. Kissinger,Eileen Kraemer,Wei Li,Flora J. Logan,John A. Miller,Siddhartha Mitra,Peter J. Myler,Vishal Nayak,Cary Pennington,Isabelle Phan,Deborah F. Pinney,Gowthaman Ramasamy,Matthew B. Rogers,David S. Roos,Christopher A. Ross,Dhileep Sivam,Deborah F. Smith,Ganesh Srinivasamoorthy,Christian J. Stoeckert,Sandhya Subramanian,Ryan Thibodeau,Adrian Tivey,Charles Treatman,Giles S. Velarde,Haiming Wang +43 more
TL;DR: TriTrypDB is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs, utilizing a sophisticated search strategy system.