Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference

Oxidative Stress, Inflammation, and Cancer: How Are They Linked?

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

https://minerva-access.unimelb.edu.au/bitstream/handle/11343/194901/Stockwell_Cell_review+2017.pdf

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

https://www.who.int/foodsafety/chem/2005_WHO_TEFs_ToxSci_2006.pdf

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds.

We have routinely performed transurethral surgery, which shows unique urological peculiarity, for over a hundred years. The recent developments and technological advances in urological laparoscopic surgeries are also remarkable. Nowadays, endourology consists of 4 surgical approaches; including the transurethral, laparoscopic, retroperitoneal and percutaneus approach. Herein, we describe the recent advances of endoscopic surgeries in Urology.

https://www.jstage.jst.go.jp/article/numa/67/2/67_2_96/_pdf

Endoscopic Surgery in Urology ; Endourology

A ventricular septal defect (VSD) is a common congenital heart disease, and the transcatheter technique for VSD requires practical guidance because it requires a complicated procedure. A non-obstructive angioscopy catheter system via the right ventricle successfully revealed an approximately 3-mm VSD with the shape of a rugby ball at the center of the white membranous septum of Kirklin type II in an older female with suspected coronary artery disease. A white membranous terraced septum was observed to be surrounded by a reddish ventricle. Conservative therapy was performed for her VSD because she did not meet the criteria for surgical treatment.

/pdf/demonstrating-an-adult-ventricular-septal-defect-using-non-eo8r3z0p.pdf

Demonstrating an Adult Ventricular Septal Defect Using Non-obstructive General Angioscopy

Hypothesis / aims of study The vaginal distension (VD) model is widely used to study mechanisms of injury and tissue recovery of stress urinary incontinence (SUI) 1 . Since urethral sphincter injury induced by VD usually recovers in a short period (within approximately 4 weeks), the VD model is not suitable to assess the long-term effect of various therapeutic treatments on SUI. In order to develop a novel physiological and sustained SUI model, we created a rat model of urethral sphincter injury by combination treatment of VD with bilateral ovariectomy (OVX), and examined sphincteric contractility and histology in the urethra of the model.

Development of a novel rat model of stress urinary incontinence

Text mining, one of the emerging fields of data mining, aims at acquiring useful knowledge from text data. In the asset management in finance task domain, although there exist various text data like accounting settlement or analysts' reports, few research and development have been conducted. In this paper, we will explore the feasibility to extract valuable knowledge for asset management through text mining using analyst reports as text data. We will analyze the relationship between text data and numerical data. From empirical study on the practical data, we have confirmed the effectiveness: (1) the extracted keywords are influential to the stock prices, (2) such information is more effective to the large-cap stocks, and (3) such keyword information become more valuable by using numerical information together.

Learning value-added information of asset management from analyst reports through text mining

Few modalities have the capacity to demonstrate massive or fragmented thrombi to evaluate the effect of catheter-based or systemic thrombosis for pulmonary embolism (PE). We herein present a patient who underwent a thrombectomy for PE using a non-obstructive general angioscopy (NOGA) system. Small floating mobile thrombi were aspirated using the original method, and massive thrombi were aspirated using the NOGA system. Systemic thrombosis was also monitored via NOGA for 30 minutes. Detachment of thrombi from the wall of the pulmonary artery began two minutes after infusion of a recombinant tissue plasminogen activator (rt-PA). Six minutes after thrombolysis, the thrombi lost their erythematous color, and the white thrombi gradually floated and dissolved. NOGA-guided selective pulmonary thrombectomy and NOGA-monitored systemic thrombosis contributed to improved patient survival. Rapid systemic thrombosis for PE using rt-PA was also demonstrated by NOGA.

/pdf/angioscopy-guided-selective-pulmonary-thrombectomy-and-2xy94g22.pdf

Satoru Takahashi

Papers

Endoscopic Surgery in Urology ; Endourology

Demonstrating an Adult Ventricular Septal Defect Using Non-obstructive General Angioscopy

Development of a novel rat model of stress urinary incontinence

Learning value-added information of asset management from analyst reports through text mining

Angioscopy-Guided Selective Pulmonary Thrombectomy and Angioscopy-Monitored Systemic Thrombosis for a Pulmonary Embolism