S
Satoru Takahashi
Researcher at University of Tsukuba
Publications - 633
Citations - 31434
Satoru Takahashi is an academic researcher from University of Tsukuba. The author has contributed to research in topics: MAFB & Medicine. The author has an hindex of 79, co-authored 589 publications receiving 28007 citations. Previous affiliations of Satoru Takahashi include Hokkaido University & Nihon University.
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Journal ArticleDOI
Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method.
Sanae Hamanaka,Jun Ooehara,Yohei Morita,Hideo Ema,Satoru Takahashi,Atsushi Miyawaki,Makoto Otsu,Tomoyuki Yamaguchi,Masafumi Onodera,Hiromitsu Nakauchi +9 more
TL;DR: Using the random segregation of provirus (RSP) method, a transgenic mouse line expressing a red/orange fluorescent protein, Kusabira Orange (KuO), is generated that likely will prove useful for study of hematopoiesis that includes erythropoieis and megakaryopoiedis.
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Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation.
Kenta Kikuchi,Mayumi Iida,Naoki Ikeda,Shigetaka Moriyama,Michito Hamada,Satoru Takahashi,Hiroshi Kitamura,Takashi Watanabe,Yoshinori Hasegawa,Koji Hase,Takeshi Fukuhara,Takeshi Fukuhara,Hideyo Sato,Eri H. Kobayashi,Takafumi Suzuki,Masayuki Yamamoto,Masato Tanaka,Kenichi Asano +17 more
TL;DR: This study finds that CD169+ macrophages change their phenotype by regulating the level of a transcription factor Maf both in vitro and in vivo in C57BL/6J mice.
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Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need
Minjeong Park,Chika Miyoshi,Tomoyuki Fujiyama,Miyo Kakizaki,Aya Ikkyu,Takato Honda,Jinhwan Choi,Fuyuki Asano,Seiya Mizuno,Satoru Takahashi,Masashi Yanagisawa,Masashi Yanagisawa,Hiromasa Funato,Hiromasa Funato +13 more
TL;DR: Whether the PKA phosphorylation sites of SIK1 and SIK2 are involved in sleep regulation by generating Sik1 S577A and Sik2 S587A mice is examined, suggesting that PKA-SIK signaling is involved in the regulation of sleep need.
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Differentiation of IL-17-Producing Invariant Natural Killer T Cells Requires Expression of the Transcription Factor c-Maf.
TL;DR: It is shown that c-Maf deficiency is essential for the induction of IL-17-producing iNKT (iNKT17) cells by IL-6, TGF-β, and IL-1 β, and the optimal expression of RORγt in iN KT17 cells, and is a potential therapeutic target in inKT17 cell-mediated inflammatory disease.
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Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7α (Fbw7α) Causes Hepatosteatosis through Kruppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor γ2 (PPARγ2) Pathway but Not SREBP-1c Protein in Mice
Shin Kumadaki,Tadayoshi Karasawa,Takashi Matsuzaka,Masatsugu Ema,Yoshimi Nakagawa,Masanori Nakakuki,Ryo Saito,Naoya Yahagi,Hitoshi Iwasaki,Hirohito Sone,Kazuhiro Takekoshi,Shigeru Yatoh,Kazuto Kobayashi,Akimitsu Takahashi,Hiroaki Suzuki,Satoru Takahashi,Nobuhiro Yamada,Hitoshi Shimano +17 more
TL;DR: Hepatic Fbw7α contributes to normal fatty acid and triglyceride metabolism, functions that represent novel aspects of this cell growth regulator.