S
Satoshi Endo
Researcher at Gifu Pharmaceutical University
Publications - 167
Citations - 2794
Satoshi Endo is an academic researcher from Gifu Pharmaceutical University. The author has contributed to research in topics: Reductase & Aldo-keto reductase. The author has an hindex of 26, co-authored 152 publications receiving 2237 citations. Previous affiliations of Satoshi Endo include Gifu University.
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Journal ArticleDOI
Kinetic studies of AKR1B10, human aldose reductase-like protein: Endogenous substrates and inhibition by steroids
Satoshi Endo,Toshiyuki Matsunaga,Hiroaki Mamiya,Chisato Ohta,Midori Soda,Yukio Kitade,Kazuo Tajima,Hai-Tao Zhao,Ossama El-Kabbani,Akira Hara +9 more
TL;DR: A novel role of AKR1B10 is proposed in controlling isoprenoid homeostasis that is important in cholesterol synthesis and cell proliferation through salvaging isopranoid alcohols, as well as its metabolic regulation by endogenous steroids.
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Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.
TL;DR: The involvement of up-regulated AKR1C1, AKR 1C3 and proteasome in CDDP resistance of colon cancers and support a chemotherapeutic role for their inhibitors are suggested.
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Aldo–Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers
TL;DR: The human aldo–keto reductase AKR1B10 has been recently reported to be significantly up-regulated in some cancer cell lines acquiring resistance toward chemotherapeutic agents, suggesting the validity of the enzyme as a chemoresistance marker.
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Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells
Akira Ikari,Akira Ikari,Ryo Watanabe,Tomonari Sato,Saeko Taga,Shun Shimobaba,Masahiko Yamaguchi,Yasuhiro Yamazaki,Satoshi Endo,Toshiyuki Matsunaga,Junko Sugatani +10 more
TL;DR: It is suggested that nuclear distribution of claudin-2 is up-regulated by dephosphorylation and claudIn-2 serves to retain ZONAB and cyclin D1 in the nucleus, resulting in the enhancement of cell proliferation in lung adenocarcinoma cells.
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Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells
Hiroyuki Sonoki,Tomonari Sato,Satoshi Endo,Toshiyuki Matsunaga,Masahiko Yamaguchi,Yasuhiro Yamazaki,Junko Sugatani,Akira Ikari +7 more
TL;DR: It is found that quercetin, a flavonoid present in fruits and vegetables, time- and concentration-dependently decreases claudin-2 expression in lung adenocarcinoma A549 cells.